WHO CLASSIFICATION OF TUMOURS OF HAEMATOPOIETIC AND LYMPHOID TISSUES, REVISED 4TH EDITION

1 Introduction and overview of the classifi cation of the myeloid neoplasms 15
2 Myeloproliferative neoplasms 29
3 Mastocytosis 61
4 Myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement 71
5 Myelodysplastic/myeloproliferative neoplasms 81
6 Myelodysplastic syndromes 97
7 Myeloid neoplasms with germline predisposition 121
8 Acute myeloid leukaemia and related precursor neoplasms 129
9 Blastic plasmacytoid dendritic cell neoplasm 173
10 Acute leukaemias of ambiguous lineage 179
11 Introduction and overview of the classifi cation of the lymphoid neoplasms 189
12 Precursor lymphoid neoplasms 199
13 Mature B-cell neoplasms 215
14 Mature T- and NK-cell neoplasms 345
15 Hodgkin lymphomas 423
16 Immunodefi ciency-associated lymphoproliferative disorders 443
17 Histiocytic and dendritic cell neoplasms 465

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised 4th Edition Volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome.

Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis and predictive factors.

This classification, prepared by 132 authors from 23 countries, contains about 1300 colour images and tables, and more than 4500 references.