2:Organization of Genetic Variation
3:Inbreeding and Population Structure
4:Mutation, Gene Conversion, and Migration
5:Natural Selection in Large Populations
6:Random Genetic Drift in Small Populations
7:Molecular Population Genetics
8:Population Genetics of Complex Traits
9:Complex Traits in Natural Populations
A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention.
This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.
• Provides a concise, accessible introduction to understanding evolution and genetics/genomics at the population level
• Includes a broad taxonomic range of examples - human, animal, plant, and microbe population genetics and genomics
• Places emphasis on the history of the subject as well as the clear exposition of mathematical models
• Consolidates learning with numerous in-text problems for students to apply concepts as they encounter them