ANTICOAGULATION THERAPY

1. Introduction
2. Warfarin
3. Unfractionated Heparin and Low-Molecular-Weight Heparin
4. Parenteral Anticoagulants: Direct Thrombin Inhibitors and Pentasaccharides
5. Direct Oral Anticoagulants
6. Anticoagulation Reversal
7. Transitioning Between Anticoagulants
8. The Anticoagulation Clinic
9. Perioperative Management of Anticoagulants
10. Acute Coronary Syndromes
11. Antithrombotic Therapy for Patients with Atrial Fibrillation
12. Anticoagulant Strategies for Electrophysiology Procedures
13. Anticoagulation for Cardiac Prosthetic Devices: Prosthetic Heart Valves, Left Ventricular Assist Devices, and Septal Closure Devices
14. Anticoagulation in Venous Thromboembolism
15. Thrombophilic States
16. Thrombophilia Testing
17. Heparin-Induced Thrombocytopenia
18. Anticoagulation Therapy in Pregnant Patients
19. Anticoagulation in the Elderly
20. Anticoagulation in the Patient with Cancer

This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.

Features
• Presents the latest evidence and guidelines that support the use of anticoagulant therapy for various clinical scenarios
• Reviews the pharmacologic properties of various anticoagulants
• Details the clinical applications of anticoagulant therapy

Autores
• Joe F. Lau MD, PhD, FACC, FASE, FSVM, RPVI. Associate Professor of Cardiology. Zucker School of Medicine at Hofstra/Northwell. Director of Vascular Medicine. Director of Non-Invasive Vascular Laboratory. Department of Cardiology. Northwell Health. New Hyde Park, NY
• Geoffrey D. Barnes, MD, MSc. Assistant Professor. Frankel Cardiovascular Center at the University of Michigan. Department of Internal Medicine. Division of Cardiovascular Medicine. Ann Arbor, MI
• Michael B. Streiff, MD. Associate Professor of Medicine and Pathology. Division of Hematology. Department of Medicine. The Johns Hopkins University School of Medicine. Baltimore, MD