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141,28 ۥ Introduction
Goals
Developmental Stages
Materials and Methods
Acknowledgments
References
• Chapter 1. Skin and Mammary Gland
Abstract
Introduction
Skin (Histologic Anatomy and Development)
Histologic Anatomy of the Skin
Postnatal Development of the Skin
Mammary Gland
References
• Chapter 2. Musculoskeletal System
Abstract
Introduction
Skeletal Muscle
Bone
References
• Chapter 3. Nervous System
Abstract
Introduction
Brain
Spinal Cord
Peripheral Nerves
References
• Chapter 4. Respiratory System
Abstract
Introduction
Embryologic Development of the Respiratory Tract
Nasal Cavity
Larynx and Trachea
Bronchi, Bronchioles, and Terminal Bronchioles
Lung
References
• Chapter 5. Gastrointestinal Tract
Abstract
Introduction
Control of Postnatal Development
Tongue
Esophagus
Stomach
Small Intestine
Large Intestine
References
• Chapter 6. Liver, Exocrine Pancreas, and Salivary Glands
Abstract
Introduction
Liver
Exocrine Pancreas
Salivary Glands
References
• Chapter 7. Female Reproductive System
Abstract
Introduction
Ovary
Oviduct
Uterus
Cervix
Vagina
References
• Chapter 8. Male Reproductive System
Abstract
Introduction
Testes
Epididymis
Vas Deferens
Seminal Vesicles
Prostate Gland
References
• Chapter 9. The Endocrine System
Abstract
Introduction
Pituitary Gland
Pancreatic Endocrine Tissue
Thyroid Gland
Parathyroid Gland
Adrenal Gland
References
• Chapter 10. Immune System
Abstract
Introduction
Bone Marrow
Thymus
Spleen
Lymph Nodes
Mucosa-Associated Lymphoid Tissue (MALT)
Summary
References
• Chapter 11. Hematopoietic System
Abstract
Hematopoiesis
References
• Chapter 12. The Eye and Harderian Gland
Abstract
Introduction
Embryological Development of the Eye
Postnatal Development of the Eye
References
• Chapter 13. Urinary System
Abstract
Introduction
Kidney
Lower Urinary Tract
References
• Chapter 14. Cardiovascular System
Abstract
Introduction
Transition From Fetal to Postnatal Circulation
Heart
Great Vessels
References
• Index
Features:
• Written and edited by highly experienced, board-certified toxicologic pathologists
• Includes more than 700 high-resolution microscopic images from organs that are typically examined in safety assessment toxicology studies
• Detailed figure legends and chapter narratives present the salient features of each organ at each time interval
• Figures are available for further study via Elsevier’s Virtual Microscope, which allows viewing of microscopic images at higher magnification
• Valuable resource for toxicologic pathologists who are confronted with interpretation of lesions in juvenile rats in situations where age-matched concurrent controls are not available for comparison, e.g., with unscheduled decedents
• Figures are available for further study on ScienceDirect with Virtual Microscope, which allows viewing of microscopic images at higher magnification
Authors
• George A Parker, WIL Research Laboratories, LLC, Ashland, OH, USA.
• Catherine A. Picut, WIL Research Laboratories, LLC, Ashland, OH, USA