BIOCHEMISTRY OF SIGNAL TRANSDUCTION AND REGULATION. 5TH EDITION

CHAPTER 1. Basics of Cell Signaling (Pages: 1-26)
CHAPTER 2. Structural Properties, Regulation and Posttranslational Modification of Signaling Proteins (Pages: 27-102)
CHAPTER 3. Organization of Signaling (Pages: 103-128)
CHAPTER 4. The Regulation of Gene Expression (Pages: 129-208)
CHAPTER 5. RNA Processing, Translational Regulation, and RNA Interference (Pages: 209-250)
CHAPTER 6. Signaling by Nuclear Receptors (Pages: 251-290)
CHAPTER 7. G Protein-Coupled Signal Transmission Pathways (Pages: 291-368)
CHAPTER 8. Intracellular Messenger Substances: “Second Messengers” (Pages: 369-416)
CHAPTER 9. Ser/Thr-Specific Protein Kinases and Protein Phosphatases (Pages: 417-472)
CHAPTER 10. Signal Transmission via Transmembrane Receptors with Tyrosine-Specific Protein Kinase Activity (Pages: 473-534)
CHAPTER 11. Signal Transmission via Ras Proteins (Pages: 535-572)
CHAPTER 12. Intracellular Signal Transduction: The MAP Kinase Pathways (Pages: 573-592)
CHAPTER 13. Membrane Receptors with Associated Tyrosine Kinase Activity (Pages: 593-630)
CHAPTER 14. Other Transmembrane Receptor Classes: Signaling by TGF-ß Receptors, TNF Receptors, Toll Receptors, and Notch (Pages: 631-660)
CHAPTER 15. Cell-Cycle Control by External Signaling Pathways (Pages: 661-714)
CHAPTER 16. Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes (Pages: 715-776)
CHAPTER 17. Apoptosis (Pages: 777-800)
Index (Pages: 801-815)

Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on "the Krauss" to find their way through the bewildering complexity of biological signaling pathways.

Author
Gerhard Krauss is Professor of Biochemistry at the University of Bayreuth (Germany). His resarch is centered on the mechanism of interaction of DNA binding proteins and their target DNA. He is also a gifted teacher and textbook author, and for many years has been the head of the university education committee of the German Society of Biochemistry and Molecular Biology (GBM).