BIOPOLYMERS FOR MEDICAL APPLICATIONS

• Biopolymers in Regenerative Medicine: Overview, Current Advances, and Future Trends
• Application of Natural, Semi-synthetic, and Synthetic Biopolymers Used in Drug Delivery Systems Design
• Polysaccharide Based Biomaterials
• Biopolymers in the Prevention of Dental Erosion
• Drug Carriers by Liposomes Physically Coated with Peptides
• Biopolymers for in vitro Tissue Model Biofabrication
• Medical Application of Polyampholytes
• Biomedical Applications of Recombinant Proteins and Derived Polypeptides
• Cellulose Nanofibers for Biomedical Applications
• Modelling and Simulation of Biological Systems in Medical Applications
• High-Order Perturbation Theory Models of Drug-Target Interactomes for Proteins Expressed on Networks of Hippocampus Brain Region of Alzheimer Disease Patients
• Structural Modeling for DNA and RNA Bindings to Breast Anticancer DrugTamoxifen and its Metabolites
• Dynamic Analysis of Backbone-Hydrogen-Bond Propensity for Protein Binding and Drug Design
• Molecular Dynamics Simulations and Comparison of Two New and High Selective Imprinted Xerogels.

This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.

Features
• Highlights the advantages and disadvantages of various models, theories and techniques.
• Covers modern topics related to biopolymers and biomaterials.
• Focuses on the most common and most utilized techniques.

Authors
• Juan M. Ruso is Professor of the Department of Applied Physics at University of Santiago de Compostela. Ruso’s scientific contributions are from such diverse areas as soft matter, biophysics, materials, and nanotechnology.
Ruso is the author of more than 150 research papers. He is co-author of the textbook “Introduction to Electromagnetism” (in Spanish) and co-editor of “Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science.” He has held Visiting Research and Visiting Professor positions in different universities around the world, including University of Manchester, Columbia University, Universidad Nacional Autónoma de México, Universidad Nacional del Sur, and Universidade de Sao Paulo.
• Paula V. Messina is currently Professor of Physical Chemistry at the Universidad Nacional del Sur, Argentina and an independent researcher at CONICET-Argentina.
Messina is the author of more than 100 research publications and Guest Editor with the journal Current Topics in Medicinal Chemistry. From 2000 to the present, she has worked on several research topics related to the study of self-assembled systems, such as amphiphilic aggregates (liquid crystals, emulsions, micro emulsions, vesicles, liposomes, and organized monolayers), and in the study of new systems with potential applications in the transport of active principles and their interaction with biological units. Her investigations eventually turned to the design and preparation of various types of organized and hierarchical inorganic and biological structures templated by self-assembly techniques. In 2010, she created her own research group, “Nanostructured materials group,” whose investigations have a particular relationship to the development of nanostructured materials with an emphasis on bio-medical applications: implants, biomarkers and drug transport.