BLOCK'S DISINFECTION, STERILIZATION, AND PRESERVATION. 6TH EDITION

• PART I: INTRODUCTION
1. Historical Perspective . .1
2. Defi nition of Terms 9
• PART II: FUNDAMENTAL PRINCIPLES OF ACTIVITY
3. Microorganisms and Resistance .23
4. Bacterial Resistance to Biocides .44
5. Principles of Antimicrobial Activity . . .68
6. The Impact of Formulary Components on Antimicrobial Products .120
7. Kinetics of the Inactivation of Microorganisms .140
8. Importance and Processes of Cleaning . .160
• PART III: DISINFECTION BY ANTIMICROBIAL TYPES
9. Ultraviolet Disinfection . . .171
10. Nonionizing Radiation: Microwave Radiation, Infrared Radiation, and Pulsed Light 192
11. Microbial Inactivation Kinetics and Heat Disinfection 205
12. Acids and Alkalis 243
13. Antimicrobial Dyes . .252
14. Essential Oils . . .268
15. Chlorine and Chlorine Compounds .280
16. Iodine and Iodine-Containing Compounds 306
17. Bromine and Bromine-Releasing Biocides . . .332
18. Peroxygen Compounds . .352
19. Alcohols . . .384
20. Phenolic Compounds 408
21. Surface-Active Agents . . .437
22. Chlorhexidine . .477
23. Aldehydes .507
24. Copper Alloy Surfaces Kill Bacteria and Reduce Infections . . .538
25. Silver and Silver Nanoparticles .549
26. Peptides, Enzymes, and Bacteriophages .559
27. Chlorine Dioxide 570
• PART IV: STERILIZATION BY ANTIMICROBIAL TYPES
28. Sterilization and Depyrogenation by Heat . . .589
29. Sterilization and Preservation by Radiation . .609
30. Sterile Filtration of Liquids and Gases . . .630
31. Ethylene Oxide Sterilization . . .660
32. Disinfection and Sterilization With Hydrogen Peroxide . .671
33. Disinfection and Sterilization Using Ozone . . .684
34. Plasma Sterilization . .702
35. Nitrogen Dioxide . . .726
36. Formaldehyde . .756
• PART V: PRESERVATION
37. Prevention of Infection From Food and Water 765
38. Preservation of Industrial Products and Processes . .780
39. Preservation of Pharmaceutical Dosage Forms . .795
40. Cosmetic Preservatives and Preservation . . .822
41. Sterile Packaging 835
• PART VI: MEDICAL AND HEALTH- RELATED APPLICATIONS
42. Hand Hygiene . .859
43. Surgical Antisepsis . .879
44. Infection Prevention for Skin and Burns . .899
45. Oral and Mucous Membrane Treatments 916
46. Laundry Hygiene 930
47. Processing of Reusable Medical Devices . . .938
48. Targeted Decontamination of Environmental Surfaces in Everyday Settings . . .960
49. Basic Principles of Infection Prevention and Control . . .979
50. Disinfection and Sterilization of Living and Scaffold Tissue Engineered Medical Products . . .994
51. Sterilization, Disinfection, and Asepsis in Dentistry 1008
52. Disinfection and Biosecurity in the Prevention and Control of Disease in Veterinary Medicine . . . 1034
53. Disinfection of Contact Lenses 1107
54. Infectious Waste Management, Treatment, and Disposal 1125
55. Reprocessing and Remanufacturing of Single-Use Medical Devices . .1145
• PART VII: INDUSTRIAL AND RESEARCH APPLICATIONS
56. Food- and Waterborne Microorganisms 1153
57. Groundwater Purifi cation . . . 1183
58. Aseptic Processing and Facilities for the Control of Microbial Contamination .1200
59. Safe Handling of Biological Agents in the Laboratory 1214
60. Control and Monitoring of Microbiological Quality in Nonsterile Manufacturing Facilities .1229
• PART VIII: METHODS OF TESTING
61. Disinfectant Effi cacy Testing . .1241
62. Standard Microbiological Methods for Antimicrobial Products in North America .1252
63. Antimicrobial Test Methods in the European Union . . .1269
64. Bioburden Assessment and Tests for Sterility . . .1277
65. Biological Indicators, Chemical Indicators, and Parametric Release 1297
• PART IX: MISCELLANEOUS TOPICS
66. Bacterial Endotoxin .1307
67. Biofi lm and Biofi lm Control . . .1320
68. Prions 1337
69. Fungal Contamination in the Built Environment: Shipping and Storage1352
70. Regulation of Preservation, Disinfection, and Sterilization Agents, Equipment, and Processes . . .1360
71. Federal Regulation of Liquid Chemical Germicides and Healthcare Sterilization by the US Food and Drug Administration .1379
72. Regulation of Antimicrobial Pesticides by the US Environmental Protection Agency .1380
73. Antimicrobial Surfaces . .1387
74. Nanotechnology for Disinfection and Sterilization . . .1404
S u b je c t I n dex 1419

With more international contributors than ever before, Block’s Disinfection, Sterilization, and Preservation, 6th Edition, is the first new edition in nearly 20 years of the definitive technical manual for anyone involved in physical and chemical disinfection and sterilization methods. The book focuses on disease prevention—rather than eradication—and has been thoroughly updated with new information based on recent advances in the field and understanding of the risks, the technologies available, and the regulatory environments.

• International authorship has expanded, and editors and contributors have extensive backgrounds in antimicrobial control of infection risks.
• Discusses new understandings of microbes and how to manage them through disinfection and prevention.
• Content addresses chemical types of disinfectants/sterilants, physical disinfection/sterilization technologies, test methodologies, and more.
• eBook features a selection of full-color figures.
• Ideal for academic investigation as well as for practical use across industrial and regulatory applications.

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