BONE AND JOINT INFECTIONS. FROM MICROBIOLOGY TO DIAGNOSTICS AND TREATMENT

1. Native joint arthritis in children
a. Introduction
b. Epidemiology/microbiology
c. Pathogenesis and risk factors
d. Clinical features
e. Laboratory investigation
f. Imaging procedures
g. Differential diagnosis
h. Management (including local interventions and antibiotic treatment)

2. Native joint arthritis in adults
a. Introduction
b. Epidemiology/microbiology
c. Pathogenesis and risk factors
d. Clinical features
e. Laboratory investigation
f. Imaging procedures
g. Differential diagnosis
h. Management (including local interventions and antibiotic treatment)

3. Arthritis of syndesmosis (pubic syndesmosis, sacroiliitis, sternoclavicular joint)
a. Introduction
b. Epidemiology/microbiology
c. Risk factors (special population: IVDU etc)
d. Clinical features
e. Laboratory investigation
f. Imaging procedures
g. Management (including local interventions and antibiotic treatment)

4. Periprosthetic joint infection: general aspects
a. Introduction
b. Definition
c. Classification
d. Pathogenesis of biofilm infections
e. Diagnostic algorithm
f. Laboratory investigation (infectious parameters, sonication, histology, culture, moleculardiagnostics)
g. Imaging procedures
h. Management: surgical intervention according to algorithm and antibiotic treatment (iv, pos, duration)
i. Prophylaxis (antibiotics and infection control measures)

5. PJI after total hip and knee arthroplasty
a. Introduction incl. differential diagnosis
b. Risk factors for infection (incl. problem of superficial vs deep surgical site infection; exogenous infection:non healing wound, secondary wound dehiscence, VAC; hematogenous infection: UTI, dental work, sepsis etc.)
c. Clinical features
d. Specific laboratory investigation (synovial fluid cell counts, frozen section
e. Imaging procedures
f. Management (surgical interventions and antibiotic treatment)
g. Specific problems in hip PJI (e.g. lateral or medial surgical approach, one stage vs two stage exchange, role of spacer etc.)
h. Specific problems in knee PJI (e.g. arthroscopic vs. open lavage etc.)
i. Instructive cases

6. PJI after shoulder arthroplasty
a. Introduction incl. risk factors
b. Microbiology
c. Clinical features
d. Diagnostic procedures
e. Management (surgical interventions and antibiotic treatment)
f. Instructive cases

7. PJI after elbow arthroplasty
a. Introduction incl. risk factors
b. Microbiology
c. Clinical features
d. Diagnostic procedures
e. Management (surgical interventions and antibiotic treatment)
f. Instructive cases

8. PJI after ankle arthroplasty
a. Introduction incl. risk factors
b. Microbiology
c. Clinical features
d. Diagnostic procedures
e. Management (surgical interventions and antibiotic treatment)
f. Instructive cases

OSTEOMYELITIS

1. Classification
2. Microbiology
a) Spectrum of microorganisms in bone infection
b) Conventional microbiological diagnostics
c) Molecular diagnostic procedures
3. Acute osteomyelitis in adults (vertebral osteomyelitis)
a) Introduction
b) Pathogenesis
c) Clinical features
d) Laboratory investigation
e) Imaging procedures
f) Management (Antimicrobial and surgical therapy)

4. Acute osteomyelitis in children (long bone osteomyelitis)
a) Introduction
b) Pathogenesis
c) Clinical features
d) Laboratory investigation
e) Imaging procedures
f) Management (Antimicrobial and surgical therapy)

5. Subacute osteomyelitis (brucellosis, tuberculosis)
a) Introduction
b) Epidemiology
c) Clinical features
d) Laboratory investigation
e) Imaging procedures
f) Management (Antimicrobial and surgical therapy)

6. Chronic osteomyelitis
a) Introduction
b) Pathogenesis
c) Clinical features
d) Laboratory investigation
e) Imaging procedures
f) Management (Antimicrobial and surgical therapy)

7. Osteomyelitis of the jaw
a) Introduction
b) Classification
c) Clinical features
d) Laboratory investigation
e) Imaging procedures
f) Management (Antimicrobial and surgical therapy)


8. Implant-associated osteomyelitis of the long bones
a) Introduction incl. risk factors (classification of open fractures)
b) Microbiology
c) Clinical features
d) Diagnostic procedures
e) Management (surgical interventions and antibiotic treatment)
f) Instructive cases

9. Implant-associated vertebral osteomyelitis
a) Introduction incl. risk factors
b) Microbiology
c) Clinical features
d) Diagnostic procedures
e) Management (surgical interventions and antibiotic treatment)
f) Instructive cases

10. Postoperative sternum osteomyelitis
a) Introduction incl. risk factors
b) Microbiology
c) Clinical features
d) Diagnostic procedures
e) Management (surgical interventions and antibiotic treatment)
f) Instructive cases

Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution.

Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons.

Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.