BRAIN METASTASES. ADVANCED NEUROIMAGING

1. Prevalence of Brain Metastases
2. The Mechanism of Development of Brain Metastases
3. Clinical Symptoms
4. Basic Principles of Treatment of Brain Metastases
5. Introduction to Neuroimaging Techniques in the Diagnosis of Brain Cancer Metastases
6. Radiography
7. Cerebral Angiography
8. Computed Tomography (CT)
9. Magnetic Resonance Imaging (MRI)
10. Positron Emission Tomography (PET)
11. Introduction to Metastases of Malignant Tumors in the Brain
12. Lung Cancer (LC)
13. Breast Cancer (BC)
14. Melanoma
15. Renal Cell Carcinoma (RCC)
16. Colorectal Cancer (CRC)
17. Stomach Cancer (SC)
18. Esophageal Cancer (EC)
19. Pancreatic Cancer (PC)
20. Prostate Cancer (PrC)
21. Testicular Cancer
22. Uterine Cancer (UC)
23. Ovarian Cancer
24. Thyroid Cancer
25. Rare Forms of Cancer with Metastases in the Brain
26. Metastases in the Brain from an Unknown Primary Origin
27. Introduction to Differential Diagnosis of Metastases in the Brain and Other Lesions
28. Gliomas
29. Oligodendroglioma (ODG)
30. CNS Lymphoma
31. Meningioma
32. Hemangiopericytoma
33. Hemangioblastoma
34. Cavernous Angiomas, Cavernous Malformations
35. Tumors of Sellar and Parasellar Region
36. Tumors of the Pineal Region
37. Orbital Tumors
38. Orbital Sarcoidosis
39. Intracranial Infection
40. Parasitic Infestations
41. Demyelinating Diseases
42. Traumatic Brain Injury
43. Fungal Infections (Mycoses) of CNS

This book describes the role of advanced neuroimaging techniques in characterizing the changes in tissue structure in patients with brain metastases. On a large number of newly recognized CT, MRI, and PET characteristics of brain metastases from different primary tumors are highlighted, thereby elucidating the potential differential diagnostic role of CT perfusion imaging, MR spectroscopy, MR diffusion-weighted imaging, MR susceptibility-weighted imaging, and PET with different radiopharmaceuticals. For example, the different manifestations of metastases of melanoma, renal cell carcinoma, and ovarian cancer on MRI and CT perfusion imaging are described, and the role of MR susceptibility-weighted imaging in the differential diagnosis of glioblastoma multiforme and metastatic tumors is clarified. Metastases of colon cancer have shown a special manifestation on T2 weighted images. The book also presents novel findings regarding pathogenesis and tumor biology and describes qualitative and quantitative changes in tumor tissue and alterations in brain white matter due to surrounding tumor growth.
Neuroradiologists and others, including neurosurgeons, neurologists, and nuclear medicine physicians, will find that this book offers a fascinating insight into the ways in which newly available data on structural, hemodynamic, and metabolic changes are enriching the neuroimaging of brain metastases.

Features
• Presents new advanced neuroimaging findings
• Analyzes the role of imaging methods in the differential diagnosis of primary tumors
• Describes changes in tumor tissues and white matter of the brain

Authors
• Mikhail Dolgushin, M.D., Ph.D., Professor of Russian Academy of Science, Head of PET department, Russian Oncology Scientific Center, Moscow. Professor Dolgushin is the author of more than 100 scientific publications.
• V.N. Kornienko, MD, PhD, is a famous Russian neuroradiologist and former Head of the Neuroimaging Department of the Burdenko Neurosurgical Institute. He is an academician of the Russian Academy of Science and a full member of the Russian and American Societies of Neuroradiology. Professor Kornienko is the author of 21 monographs (including two published by Springer) in the field of neuroradiology as well as more than 500 scientific publications.
• I.N. Pronin, MD, PhD, is head of the Neuroimaging Department at the Burdenko Neurosurgical Institute of the Russian Ministry of Health. Professor Pronin is an Associate Member of the Russian Academy of Science. He is the author of 14 monographs in the field of neuroradiology (including two published by Springer) and more than 350 scientific publications.