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• Part 1. Foundations of Cardiovascular Medicine
1. Cardiovascular Disease: Past, Present, and Future
2. Global Burden and Epidemiology of Cardiovascular Disease
3. Impact of the Environment on Cardiovascular Health
4. Clinical Trials in Cardiovascular Medicine
5. Clinical Decision Making in Cardiology
6. Impact of Healthcare Policy on Quality and Outcomes of Cardiovascular Disease
• Part 2. Individualizing Approaches to Cardiovascular Disease
7. Applications of Genetics to Cardiovascular Medicine
8. Proteomics and Metabolomics in Cardiovascular Medicine
9. Principles of Drug Therapeutics, Pharmacogenomics, and Biologics
10. Biomarkers and Use in Precision Medicine
11. Artificial Intelligence in Cardiovascular Medicine
12. Wearable Devices in Cardiovascular Medicine
• Part 3. Evaluation of the Patient
13. History and Physical Examination: An Evidence-Based Approach
14. Electrocardiography
15. Exercise Physiology and Testing
16. Echocardiography
17. The Chest Radiograph in Cardiovascular Disease
18. Nuclear Cardiology
19. Cardiovascular Magnetic Resonance Imaging
20. Cardiac Computed Tomography
21. Coronary Angiography and Intravascular Imaging
22. Invasive Cardiac Hemodynamics
23. Anesthesia and Noncardiac Surgery in Patients with Heart Disease
• Part 4. Preventive Cardiology
24. The Vascular Biology of Atherosclerosis
25. Primary Prevention of Cardiovascular Disease
26. Systemic Hypertension: Mechanisms, Diagnosis, and Treatment
27. Lipoprotein Disorders and Cardiovascular Disease
28. Tobacco and Nicotine Products in Cardiovascular Disease
29. Nutrition and Cardiovascular and Metabolic Diseases
30. Obesity: Medical and Surgical Management
31. Diabetes and the Cardiovascular System
32. Exercise and Sports Cardiology
33. Comprehensive Cardiac Rehabilitation
34. Integrative Approaches to the Management of Patients with Heart Disease
• Part 5. Atherosclerotic Cardiovascular Disease
35. Approach to the Patient with Chest Pain
36. Coronary Blood Flow and Myocardial Ischemia
37. ST-Elevation Myocardial Infarction: Pathophysiology and Clinical Evolution
38. ST-Elevation Myocardial Infarction: Management
39. Non-ST Elevation Acute Coronary Syndromes
40. Stable Ischemic Heart Disease
41. Percutaneous Coronary Intervention
42. Diseases of the Aorta
43. Peripheral Artery Diseases
44. Treatment of Noncoronary Obstructive Vascular Disease
45. Prevention and Management of Ischemic Stroke
• Part 6. Heart Failure
46. Mechanisms of Cardiac Contraction and Relaxation
47. Pathophysiology of Heart Failure
48. Approach to the Patient With Heart Failure
49. Diagnosis and Management of Acute Heart Failure
50. Management of Heart Failure Patients With Reduced Ejection Fraction
51. Heart Failure with a Preserved Ejection Fraction
52. The Dilated, Restrictive, and Infiltrative Cardiomyopathies
53. Cardiac Amyloidosis
54. Hypertrophic Cardiomyopathy
55. Myocarditis
56. Cardio-Oncology: Managing Cardiotoxic Effects of Cancer Therapies
57. Cardio-Oncology: Approach to the Patient
58. Devices for Monitoring and Managing Heart Failure
59. Mechanical Circulatory Support
60. Cardiac Transplantation
• Part 7. Arrhythmias, Sudden Death, and Syncope
61. Approach to the Patient with Cardiac Arrhythmias
62. Mechanisms of Cardiac Arrhythmias
63. Inheritable Cardiac Arrhythmias
64. Pharmacologic and Non-Pharmacologic Therapy of Cardiac Arrythmias
65. Supraventricular Arrhythmias
66. Atrial Fibrillation: Clinical Features, Mechanisms, and Management
67. Ventricular Arrhythmias
68. Bradyarrhythmias and Atrioventricular Block
69. Pacemakers and Implantable Cardioverter-Defibrillators
70. Cardiac Arrest and Sudden Cardiac Death
71. Hypotension and Syncope
• Part 8. Diseases of the Heart Valves
72. Aortic Stenosis
73. Aortic Regurgitation
74. Transcatheter Aortic Valve Replacement
75. Mitral Stenosis
76. Mitral Regurgitation
77. Tricuspid, Pulmonic, and Multivalve Disease
78. Transcatheter Therapies for Mitral and Tricuspid Valve Disease
79. Prosthetic Heart Valves
80. Cardiovascular Infections
81. Rheumatic Fever
• Part 9. Diseases of the Myocardium, Pericardium, and Pulmonary Vasculature Bed
82. Congenital Heart Disease in Adolescents and Adults
83. Catheter-Based Treatment of Congenital Heart Disease
84. Cardiomyopathies Induced by Drugs or Toxins
85. Cardiovascular Abnormalities in HIV-Infected Individuals
86. Pericardial Diseases
87. Pulmonary Embolism 88. Pulmonary Hypertension
89. Sleep-Disordered Breathing and Cardiac Disease
• Part 10. Cardiovascular Disease in Select Populations
90. Cardiovascular Disease in the Older Patient
91. Cardiovascular Disease in Women
92. Pregnancy and Heart Disease
93. Heart Disease in Racially and Ethnically Diverse Populations
• Part 11. Cardiovascular Disease and Disorders of Other Organs
94. Influenza, Pandemics, COVID-19, and Cardiovascular Disease
95. Hemostasis, Thrombosis, Fibrinolysis, and Cardiovascular Disease
96. Endocrine Disorders and Cardiovascular Disease
97. Rheumatic Diseases and the Cardiovascular System
98. Tumors Affecting the Cardiovascular System
99. Psychiatric and Behavioral Aspects of Cardiovascular Disease
100. Neuromuscular Disorders and Cardiovascular Disease
101. Interface Between Renal Disease and Cardiovascular Illness
102. Cardiovascular Manifestations of Autonomic Disorders

Current, comprehensive, and evidence-based, Braunwald’s Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area.

• Peter Libby, MD, PhD, Senior Advisor, Center for Interdisciplinary Cardiovascular Sciences, Mallinckrodt Professor of Medicine, Harvard Medical School, Senior Physician, Brigham and Women's Hospital Harvard Medical School, Boston, Massachusetts.
• Robert O. Bonow, MD, MS, Goldberg Distinguished Professor of Cardiology, Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois.
• Douglas L. Mann, MD, Lewin Chair and Professor of Medicine and Professor of Cell Biology and Physiology at Washington University in St Louis, Missouri.
• Gordon F. Tomaselli, MD, Executive Vice President; Chief Academic Officer; Dean Montefiore Medicine; Professor, Department of Medicine Einstein College of Medicine, Yeshiva University, Bronx, New York.
• Deepak Bhatt, MD, MPH, FACC, FAHA, FSCAI, FESC, Executive Director of Interventional Cardiovascular Programs, Brigham and Women’s Hospital Heart and Vascular Center; Professor of Medicine, Harvard Medical School, Boston, Massachusetts.
• Scott D. Solomon, MD, The Edward D. Frohlich Distinguished Chair, Professor of Medicine, Harvard Medical School, Senior Physician, Brigham and Women’s Hospital, Boston, Massachusetts.
• Eugene Braunwald, MD, MD(Hon), ScD(Hon), FRCP, Distinguished Hersey Professor of Medicine, Harvard Medical School, Founding Chairman, TIMI Study Group, Brigham and Women ’s Hospital,Boston, Massachusetts