CHRONIC RHINOSINUSITIS. THE MUCOSAL CONCEPT

Introduction
Epidemiology and Impact of CRS
Genetics and Epigenetics of CRS
Mechanisms
Phenotypes of CRS
Endotypes of CRS
Co-morbidities of CRS
Diagnosis
Associated Auto-Immune Disorders
Pediatric CRS
Differential Diagnosis
Medical Treatment
Surgical Approaches
Innovative Treatments and Management
Unmet Needs, Future Directions for Investigation and Innovation.

Chronic rhinosinusitis (CRS) is one of the most common health care complaints, with the prevalence of 5-12% worldwide. This book aims to present the new findings in mechanism, diagnosis and management of this widespread condition to clinical practitioners. All practical information about CRS is compiled; therefore busy clinicians would not have to perform exhaustive literature studies to diagnose CRS.

This book firstly presents the advances in the understanding of epidemiology, genetics, mechanisms, phenotypes, and immunology of this disorder. In the following chapters, details in clinical diagnosis of CRS are summarized, especially clinical characteristics in paediatric CRS. Later chapters introduce medical, surgical, and innovative treatments of CRS, with brief case studies. The role of allergies, asthma, allergic fungal rhinosinusitis, and systemic diseases are also discussed. With the illustrative figures, this book is a comprehensive and quick reference to otolaryngologists, paediatricians, family care physicians, allergists, professional clinical staff, and medical students.

Features
• Comprehensive source of information on the mechanisms, diagnosis and treatment of chronic rhinosinusitis
• Provides knowledge on precise management of the patient with rhinosinusitis
• Written by experts with a wealth of clinical experience in the field