Descuento:
-5%Antes:
Despues:
109,76 ۥ Part I Fundamental Concepts 1
1 Cytosolic and Transcriptional
2 Molecular Determinants of Human Circadian Clocks 25
3 The Suprachiasmatic Nucleus (SCN): Critical Points 37
4 Sleep and Circadian Rhythms: Reciprocal Partners in the Regulation of Physiology and Behavior 57
5 Circadian Regulation of Arousal and its Role in Fatigue 81
• Part II Circadian Regulation of Major Physiological Systems 95
6 Physiology of the Adrenal and Liver Circadian Clocks 97
7 Nutrition and Diet as Potent Regulators of the Liver Clock 107
8 The Cardiovascular Clock 119
9 Hypertension Caused by Disruption of the Circadian System: Blood Pressure Regulation at Multiple Levels 135
10 Chronobiology of Micturition 143
11 Disruption of Circadian Rhythms and Development of Type 2 Diabetes Mellitus: Contributions to Insulin Resistance and Beta]cell Failure 155
12 Circadian Clock Control of the Cell Cycle and Links to Cancer 169
13 How Shift Work and a Destabilized Circadian System may Increase Risk for Development of Cancer and Type 2 Diabetes 183
14 Circadian Rhythms in Immune Function 211
• Part III Clocks in the Central Nervous System 221
15 Circadian Clock, Reward and Addictive Behavior 223
16 How a Disrupted Clock may Cause a Decline in Learning and Memory 235
17 Circadian Rhythms in Mood Disorders 249
18 Sleep and Circadian Rhythm Disruption in Psychosis 271
19 Alzheimer’s Disease and the Mistiming of Behavior 283
20 Circadian Dysfunction in Parkinson’s Disease 295
21 Circadian Dysfunction in Huntington’s Disease 305
22 The Aging Clock 321
23 Can we Fix a Broken Clock? 337
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease.
Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration.
Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
AUTHOR
Christopher S. Colwell is a neuroscientist and Professor in the Department of Psychiatriary and Biobehavioral Sciences at the University of California, Los Angeles.
-5%
-5%
-5%
-5%
-5%
-5%
-5%
-5%
-5%
-5%
