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Biología - Bioquímica
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• Section One Reproductive Science: Fundamentals of Human Reproductive Biology 1
1 Sexual Differentiation, Gonadal Development, and Development of the External Genitalia: A Review of The Regulation of Sexual Differentiation 3
2 Male and Female Reproductive Anatomy 35
3 Fundamentals of Reproductive Endocrinology 45
4 The Ovaries, Oocytes, and Folliculogenesis 57
5 The Human Spermatozoa 65
6 The Biology of Fertilization 75
7 Human Embryo Development: From Zygote Stage to Peri-Implantation Blastocyst 93
8 The Female Reproductive Tract and Early Embryo Development: A Question of Supply and Demand 99
• Section Two Clinical Reproductive Science: Causes of Male and Female Infertility 109
9 Disorders of Male Reproductive Endocrinology 111
10 Disorders of Female Reproductive Endocrinology 125
11 Oocyte Aneuploidy and the Maternal Age Effect 133
12 Female Reproductive Pathology: Peritoneal, Uterine, and Fallopian Tube Pathologies 147
13 Pathologies of the Male Reproductive Tract 159
14 The Impact of Infections on Reproduction and Fertility 177
15 Nutrition, Fetal Health, and Pregnancy 189
16 The Embryonic Environment and Developmental Origins of Health 195
17 Lifestyle and Environmental Impacts on Fertility 205
• Section Three Clinical Reproductive Science In Practice: IVF and Assisted Reproductive Technologies 215
18 Assessing the Infertile Couple 217
19 Ovarian Stimulation Protocols 231
20 Oocyte Retrieval Techniques and Culture of Oocytes 241
21 Sperm Preparation: Strategy and Methodology 251
22 Diagnostic Semen Analysis: Uncertainty, Clinical Value, and Recent Advances 265
23 Surgical Sperm Retrieval 279
24 In Vitro Fertilization and Intracytoplasmic Sperm Injection 291
25 Morphological Assessment of Embryos in Culture 303
26 In Vitro Culture of Gametes and Embryos – The Culture Medium 317
27 Incubators in the Assisted Reproductive Technology Laboratory 333
28 Embryo Transfer Techniques and Improving Embryo Implantation Rates 341
29 Cryopreservation of Gametes and Embryos 351
30 Preimplantation Genetic Diagnosis and Screening 371
31 Long-Term Follow-Up of Children Conceived Through In Fertilization 385
Index 393

The comprehensive and authoritative guide to clinical reproductive science
The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation.
Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource:
• Offers an accessible guide to the most current research and techniques to the science of clinical reproduction
• Covers the fundamental elements of reproductive science
• Includes information on male and the female reproductive basics – everything from sexual differentiation to foetal development and parturition
• Explores the long-term health of children conceived through IVF
• Contains the newest developments in assisted reproductive technology

Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

MICHAEL CARROLL, Senior Lecturer in Reproductive Science, School of Healthcare Science, Manchester Metropolitan University, UK