COMPREHENSIVE CLINICAL ONCOLOGY. CURRENT PRACTICES. 2ND EDITION

• SECTION I COVID-19 PANDEMIC AND CANCER
Chapter 1 The COVID-19 Pandemic Impact on Cancer in Latin America / History of Oncology in Panama
Chapter 2 COVID-19 Pandemic Surgery Guidance
• SECTION II SOFT TISSUE SARCOMA
Chapter 3 Soft Tissue Sarcoma
• SECTION III HEAD AND NECK CANCER
Chapter 4 Introduction to Head and Neck Cancer
Chapter 5 Immunotherapy in Head and Neck Cancer
Chapter 6 Advances in Radiotherapy and Chemotherapy as Organ Preservation in Head and Neck Cancer
Chapter 7 Molecular Biology in Head and Neck Cancer
Chapter 8 Molecular Target Therapies in the Treatment of Head and Neck Cancer
Chapter 9 Neoplasms of the Anterior Cranial Fossa and Paranasal Sinuses
Chapter 10 Nasopharynx Cancer
Chapter 11 Oropharynx Cancer
Chapter 12 Oral Cavity Cancer
Chapter 13 Hypopharynx Cancer
Chapter 14 Larynx Cancer
Chapter 15 Malignant Tumors of the Parotid Gland
• SECTION IV THYROID CANCER
Chapter 16 Thyroid Cancer
Chapter 17 Differentiated Thyroid Cancer – Surgical Considerations
• SECTION V BREAST CANCER
Chapter 18 Breast Cancer Surgical Treatment
Chapter 19 Radical Surgical Treatment of Breast Cancer
Chapter 20 Surgical Treatment of Locally Advanced Breast Cancer – LABC
Chapter 21 Surgical Treatment of Breast Cancer After Neoadjuvant Systemic Therapy
Chapter 22 Sentinel Lymph Node Biopsy
Chapter 23 COVID-19 and Breast Cancer
• SECTION VI GASTRIC CANCER
Chapter 24 Gastric Cancer
• SECTION VII PANCREATIC CANCER
Chapter 25 Adenocarcinoma of the Pancreas
• SECTION VIII LIVER, BILIARY CANCER
Chapter 26 Historical Aspects of Liver Surgery
Chapter 27 Morphologic Anatomy
Chapter 28 Liver Regenerative Properties
Chapter 29 Hepatocellular Carcinoma – HCC
Chapter 30 Liver Metastases
Chapter 31 Gallbladder Cancer
Chapter 32 Cholangiocarcinoma
Chapter 33 Hepatoblastoma
Chapter 34 Intraoperative Ultrasonography in Liver Surgery
Chapter 35 Interventional Radiology in Hepatobiliary Pathologies
Chapter 36 Interventional Radiology – Liver Thermal Ablation
Chapter 37 Interventional Radiology – Portal Vein Embolization
Chapter 38 Interventional Radiology – Loco Regional Therapies
• SECTION IX UROLOGICAL CANCER
Chapter 39 Kidney Cancer
Chapter 40 Bladder Cancer
Chapter 41 Testicular Cancer
Chapter 42 Prostate Cancer
• SECTION X UTERINE CANCER
Chapter 43 Endometrial Polyps
Chapter 44 Ovarian Cancer Surgery
Chapter 45 Cervical Cancer
• SECTION XI COLORECTAL AND ANUS CANCER
Chapter 46 Adenocarcinoma of the Colon
Chapter 47 Rectal Cancer
Chapter 48 Anal Cancer
Chapter 49 Other Benign and Malignant Tumors of the Bowel
• SECTION XII MELANOMA
Chapter 50 Epidemiology of Melanoma in Latin America
Chapter 51 Epidemiology of Cutaneous Melanoma in South America
Chapter 52 Clinical Diagnosis of Cutaneous Melanoma
Chapter 53 Treatment of Primary Cutaneous Melanoma
Chapter 54 Ocular, Mucosal, Subungual and Leptomeningeal Melanoma
Chapter 55 Past, Present and Future of Melanoma Sentinel Lymph Node Surgery
Chapter 56 Management of Locoregional and Distant Recurrence
Chapter 57 A Potential Role for Resveratrol in Cancer Chemoprevention and Therapy
• SECTION XIII CANCER METABOLISM
Chapter 58 Targeting Cancer Metabolism

The main reason for this advancement of the second edition of our book is the covid19 pandemic and the impact on cancer patients. With all the adverse effects they make the delay in the diagnosis and treatment of cancer patients. The covid19 pandemic transformed reality. Rarely have we had cancer operations labeled as urgent, during this time it has become a norm, rather than an exception: to deal with lockdowns, delays in detection and diagnosis, delays or interruptions in cancer treatments. Surgery, unless urgent due to bleeding, perforation or obstruction, was initially limited to avoid patients or medical personnel contagion with the virus 21st century Pandemic. Lung cancer and those caused by infections will be those with the greatest increase. In the rich area of the planet, prostate, colon and breast cancer will continue to have the highest incidence. Developing countries will suffer the evils of tobacco, which generates 12 percent of their cancer cases, a percentage that continues to grow. Another 25 percent of cases find their origin in chronic diseases. Researchers estimate that by the year 2030, 1.7 million cancer cases will be diagnosed in Latin America and the Caribbean and more than one million deaths from cancer. Panama, like many other Latin American countries was affected by The covid19 Pandemic. The impact will be seen on a short, medium and long range. In order to save our patients, we are implementing a Damage control strategy(DCS) : first Stratification of our patients in Urgent, Priority and non-priorities.

The stratification can be with letters or numbers. During our General Surgery Residency Training a classification of priorities that worked well was CIDUR (Spanish Acronym for CIRUGIA DE URGENCIA) ( Dr. Enero Aviles personal communication). Multiple technologic changes, multiple virtual conferences and meetings were developed during the 2020 and the 2021. This Book has 57 chapters, the last tells the History of Oncology in Panama, linked to the History of Panama and the World.

Author
Cesar Restrepo, MD Surgical Oncologist Fellow MD Anderson Hospital and Tumor Institute, Houston Texas, USA. Corresponding Member of the Society of Surgical Oncology (SSO)