1. Acute Kidney Injury: Definitions and Epidemiology
2. Biomarkers in Pediatric Acute Kidney Injury
3. Acute Kidney Injury: Principles of Management
4. Fluid Overload and Management
5. Nutrition in Pediatric AKI and Critical Illness
6. Pharmacology of a Critically Ill Child and Drug Dosing
7. Acute Peritoneal Dialysis (PD)
8. Vascular Access in a Child with Acute Kidney Injury
9. Hemodialysis Treatment Prescription
10. Prolonged Intermittent Renal Replacement Therapy in Pediatric AKI
11. CRRT in a Sick Child
12. Renal Replacement Therapy for Patients Requiring ECMO Support
13. Plasmapheresis in Pediatric Renal Disease
14. Neonatal Acute Kidney Injury
15. Hemolytic Uremic Syndrome
16. Rapidly Progressive Glomerulonephritis
17. Acute Tubulointerstitial Nephritis
18. Drug-Induced Nephrotoxicity
19. Acute Kidney Injury in Children Following Cardiopulmonary Bypass: A Call for Action
20. Sepsis-Associated Acute Kidney Injury
21. Management of Intoxications in Pediatrics
22. RRT in Liver Failure
23. Advances in Liver Failure and Management
24. Hyperammonemia and Metabolic Diseases
25. Anticoagulation During RRT in the ICU
26. Toxic Nephropathy: Uric Acid, Rhabdomyolysis, and Tumor Lysis Syndrome
27. Outcomes of Pediatric Acute Kidney Injury
28. Long-Term Outcome of Acute Kidney Injury in Children: A Practical Approach for Follow-up
29. Advances in Paediatric Renal Replacement Therapy
This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children in intensive care.
In addition, this quick guide discusses innovations in pediatric renal replacement therapy technologies, such as plasma exchange, CARPEDIEM, NIDUS and aquadex.
This is a go-to book for intensivists, physicians and trainees working in pediatric intensive care units.
• Written by leading international experts in pediatric intensive care and pediatric nephrology
• Offers physicians detailed guidance on managing children with renal failure in intensive care units
• Provides easy-to-follow algorithms and key points in each chapter
• Includes a special section on recent technologies in pediatric renal replacement therapy, including CARPEDIEM, NIDUS and aquadex
• Dr. Sidharth Kumar Sethi is a Senior Consultant in Pediatric Nephrology and Pediatric Renal Transplant Medicine at the Kidney and Urology Institute, Medanta, India. He completed his fellowship (International Pediatric Nephrology Association Fellowship) and senior residency in Pediatric Nephrology at the All India Institute of Medical Sciences, New Delhi and the Division of Pediatric Nephrology and Transplant Immunology at Cedars Sinai Medical Centre, Los Angeles, California. He has been involved in numerous national and international meetings on pediatric acute kidney injury and pediatric dialysis. His chief interests include acute kidney injury, dialysis and pediatric renal transplantation. He has been actively involved in the care of children with all kinds of complex renal disorders, including acute kidney injury, nephrotic syndrome, tubular disorders, urinary tract infections, hypertension, chronic kidney disease. He was honored by Case Western Reserve University for his outstanding contributions to the field in 2014. He was part of an 8-member committee responsible for writing the Indian guidelines on steroid sensitive nephrotic syndrome, and member of an expert committee involved in the formulation of guidelines on pediatric renal disorders, including steroid resistant nephrotic syndrome and urinary tract infections. He has published several international papers on pediatric nephrology and chapters in nephrology textbooks. He is also Co-Convener of the Indian Society of Pediatric Nephrology- CKD Registry. He is currently Secretary of the Indian Society of Pediatric Nephrology and Editor of the Journal of Clinical Pediatric Nephrology'.
• Dr. Rupesh Raina MD, FACP, FAAP, FASN and FNKF is an Associate Professor and currently a combined Adult and Pediatric Nephrologist, Director of Medical Research in Internal Medicine at the Cleveland Clinic Foundation’s Akron General Medical Center the Akron Children’s Hospital. He is also a member of the faculty and research staff at Case Western University School of Medicine. Dr. Raina is a member of the University Council of Medicine at Northeast Ohio Medical University. His research interests include the pathophysiology and prevention of the progression of renal cystic disease; transition of nephrology care from pediatrics to adults; renal replacement therapy; and high flow ultrafiltration for management of inborn errors of metabolism. He has a particular interest in developing medical curricula and case-based workshops to enhance medical students’ and residents’ clinical knowledge. He has trained numerous scientists and clinical researchers from the United States and abroad, and has written several peer-reviewed articles, editorials and book chapters related to biomedical research and clinical activities. He is currently a member of the National Kidney Foundation’s Medical Advisory Board, fellow of the American College of Physicians the American Association of Pediatrics and the American Society of Nephrology, and fellow and board member of the National Kidney Foundation.
• Prof. Mignon McCulloch is currently a Pediatric Nephrologist and Consultant at the Pediatric Intensive Care Unit at the Red Cross War Memorial Children’s Hospital, Cape Town, as well as a Senior Lecturer at the University of Cape Town, South Africa. She is also an Honorary Consultant at Evelina London Children’s Hospital, United Kingdom.
Her interests include developing pediatric nephrology and care of critically ill children, specifically acute kidney injury (AKI), and all forms of dialysis in infants and children especially in poorly resourced regions, adolescent transition and pediatric transplantation (renal, liver and cardiac).
She is the current President Elect of the International Pediatric Transplantation Association (IPTA), Assistant Secretary of International Pediatric Nephrology Association (IPNA) and President of the African Pediatric Nephrology Association.
She is actively involved in the ‘Saving Young Lives (SYL)’ steering committee – providing hands-on training in pediatric dialysis to teams of doctors and nurses at residential courses, including bedside PD catheter insertion, vascular access training, basic resuscitation and all forms of dialysis.
• Dr. Timothy E. Bunchman is currently tenured professor and division chief, Children’s Hospital of Richmond at Virginia Commonwealth University (VCU), USA. His primary departmental program area is pediatric nephrology. He is trained in pediatric nephrology from University of Minnesota, Minneapolis. His areas of expertise and interest are pediatric transplantation, acute kidney injury, renal replacement therapy and vasculitis. He has published papers in international journals and contributed chapters in books on pediatric nephrology and pediatric critical care. He has multiple awards to his credit and has been nominated by the American Society of Pediatric Nephrology to the National Advisory Committee on Children and Disasters (NACCD). He is on editorial board of many reputed international journals including Pediatric Critical Care Medicine, Pediatric Nephrology, and Nephrology Dialysis Transplantation. He has also been an associate editor for American Journal of Kidney Diseases. He is the organizer and program director of the International Conference on Pediatric Continuous Renal Replacement Therapy (PCRRT) endorsed by International Pediatric Nephrology Association (IPNA) as well as the critical care section of the American Academy of Pediatrics (AAP).