DIAGNOSTIC PATHOLOGY. PLACENTA

PART 1: OVERVIEW GROSS AND MICROSCOPIC CHANGES
SECTION I: UMBILICAL CORD
Gross Evaluation and Normal Histology of Umbilical Cord
Knots
Umbilical Cord Edema and Thinning
Histopathologic Changes of Umbilical Cord
SECTION II: EXTRAPLACENTAL MEMBRANES
Gross Evaluation and Normal Histology of Membranes
Histopathologic Changes of Membranes
SECTION III: CHORIONIC PLATE
Gross Appearance and Normal Histology of Chorionic Plate
Histopathologic Changes of Chorionic Plate
SECTION IV: STEM VILLI
Gross Appearance and Normal Histology of Stem Villi
Histopathologic Changes of Stem Villi
SECTION V: CHORIONIC VILLI
Gross Appearance and Normal Histology of Chorionic Villi
Histopathologic Changes of Chorionic Villi
SECTION VI: DECIDUA
Gross Appearance and Normal Histology of Decidua
Histopathologic Changes of Decidua
PART 2: DIAGNOSES
Hydropic Degeneration and Hydatidiform Mole
Choriocarcinoma Placental Site Nodule and Exaggerated Placental Site
Placental Site Trophoblastic Tumor and Epithelioid Trophoblastic Tumor
SECTION I: MECONIUM
Meconium-Stained Placenta
SECTION II: AMNIOTIC FLUID INFECTION SEQUENCE
Amniotic Fluid Infection Sequence (Maternal and Fetal Inflammatory Response)
Group B Streptococcus
Other Bacterial and Mycobacterial Species
Candida Infection
SECTION III: VILLITIS ASSOCIATED WITH SPECIFIC INFECTIONS
Cytomegalovirus
Parvovirus B19
Herpes Simplex Virus
Other Viruses
Syphilis
Coccidioidomycosis
Parasitic Infections
SECTION IV: CHRONIC VILLITIS OF UNKNOWN ETIOLOGY
Cellular Composition of Chronic Inflammatory Lesions
Chronic Villitis and Intervillositis
Basal Chronic Villitis and Chronic Deciduitis
Chronic Chorioamnionitis
Eosinophilic/T-Cell Chorionic Vasculitis
SECTION V: MASSIVE PERIVILLOUS FIBRIN DEPOSITION AND MATERNAL FLOOR INFARCTION
Massive Perivillous Fibrin Deposition and Maternal Floor Infarction
SECTION VI: FETAL VASCULOPATHY
Large Vessel Fetal Vascular Occlusion
Distal Villous Lesions of Fetal Vascular Occlusion
SECTION VII: PLACENTAL ABRUPTION
Acute Abruption and Retroplacental Hematoma
Chronic Abruption
SECTION VIII: VILLOUS HYPERVASCULAR LESIONS
Chorangiosis
Chorangiomatosis
Chorangioma
SECTION IX: METASTES TO THE PLACENTA
Metastatic Tumors
SECTION X: PLACENTAL MESENCHYMAL DYSPLASIA
Placental Mesenchymal Dysplasia
PART 3: PLACENTAL EVALUATION IN SPECIAL CIRCUMSTANCES
SECTION I: CHANGES CONSISTENT WITH GESTATIONAL DIABETES
Gestational Diabetes
Placentomegaly
Distal Villous Immaturity
SECTION II: PREECLAMPSIA AND OTHER DISORDERS
Preeclampsia and Related Hypertensive Disorders
Small for Gestational Age Placenta
Distal Villous Hypoplasia
Maternal Decidual Vasculopathy
Infarcts
Extravillous Cytotrophoblast Cysts
Laminar Necrosis of Decidua
SECTION III: FETAL-MATERNAL HEMORRHAGE
Fetal-Maternal Hemorrhage
SECTION IV: PLACENTAL EVALUATION FOR SMALL FOR GESTATIONAL AGE INFANT
Placental Causes of Poor Fetal Growth
SECTION V: PLACENTAL EVALUATION IN PREMATURITY
Premature Birth
SECTION VI: PLACENTAL EVALUATION IN ABNORMAL PLACENTAL IMPLANTATION
Placenta Accreta
SECTION VII: PLACENTAL EVALUATION IN INTRAUTERINE FETAL DEMISE
1st Trimester
2nd Trimester
3rd Trimester
Recurrent Pregnancy Loss
In Utero Demise to Delivery Interval Changes
SECTION VIII: PLACENTAL EVALUATION IN MULTIPLE GESTATIONS
Complications of Monochorionic Monoamnionic Gestations
Twin Growth Discrepancy
Twin-Twin Transfusion Syndrome
After In Utero Intervention for Twin-Twin Transfusion Syndrome
Triplet and Higher Order Placenta
SECTION IX: THE POSTPARTUM HYSTERECTOMY
Evaluation of Postpartum Hysterectomy
Postpartum Hemorrhage
PART 4: APPENDIX
SECTION I: REFERENCE CHARTS FOR PLACENTAL EVALUATION
Reference Value Weights for Singleton Placentas
Reference Value Weights for Twin Placentas
Reference Value Weights for Triplet Placentas
Reference Values for Fetal and Placental Growth in Early Pregnancy
SECTION II: SAMPLE TEMPLATES FOR PLACENTAL EVALUATION
Singleton Placenta Gross Evaluation Template
Twin Placenta Gross Evaluation Template
Placenta Microscopic Evaluation Template
Placenta Triage Template

Diagnostic Pathology: Placenta is designed not only for practicing pathologists and pathologists-in-training, but for anyone interested in fields related to placental pathology. Comprehensive yet easily accessible, this medical reference book provides clear and concise information on topics including gross and microscopic changes of the placenta, common diagnoses, and placental evaluation in special circumstances.

Features:
- Approaches placental pathology from multiple lenses, including basic gross and microscopic changes; showcases diagnoses with important clinical correlations; and explains key features of the exam in specific obstetric scenarios, such as growth restriction, preeclampsia, or multiple gestations.
- Essential information is distilled into a succinct, bulleted format with numerous high-quality images to facilitate learning.
- Provides necessary reference charts and sample templates for gross and microscopic evaluation.
- Highlights recent critical diagnoses in placental pathology, such as fetal thrombotic vasculopathy or placental maturation defect.
- Provides unmatched coverage of congenital infections and the pathological examination of the cesarean and post-partum hysterectomy specimen.
- Includes correlations and illustrations of relevant fetal organ pathology for diagnosis in cases of fetal or neonatal demise.
- Comes with Amirsys eBook Advantage™, an eBook featuring expanded content, additional images, and fully searchable text.

Authors
Amy Heerema-McKenney, MD, Staff Pathologist, Cleveland Clinic Institute of Pathology and Laboratory Medicine, Cleveland, Ohio.

Monique E De Paepe, MD, MSc, Professor of Pathology and Laboratory Medicine, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island.

Edwina J Popek, DO, Professor of Pathology and Pediatrics, Baylor College of Medicine, Texas Children’s Hospital Pavilion for Women, Houston, Texas