EPIGENETICS

Features
Topics Include:
- The two forms of epigenetic modification, DNA methylation and histone acetylation, and how they take place.
- How epigenetics controls cell function, including cellular differentiation and the role of epigenetics in stem cells.
- The role of epigenetics in disease, including cancer and mental health, where there is clear evidence of epigenetic involvement.

Summary
The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does.
Epigenetics is a new textbook that brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It is a valuable source of information about all aspects of the subject for undergraduate students, graduate students, and professionals.

Table of Contents
Chapter 1. Introduction to the Study of Epigenetics
Chapter 2. The Basis of the Transcription Process
Chapter 3. DNA Packaging and Chromatin Architecture
Chapter 4. Modifying the Structure of Chromatin
Chapter 5. DNA Methylation
Chapter 6. Post-Translational Modification of Histones
Chapter 7. Histone Modification Machinery
Chapter 8. Locus-Specific Control of Histone-Modifying Enzyme Action
Chapter 9. Epigenetic Control of Cell-Specific Gene Expression
Chapter 10. Epigenetic Control of the Mitotic Cell Cycle
Chapter 11. The Epigenetic Basis of Gene Imprinting
Chapter 12. Epigenetic Control of Cellular Differentiation
Chapter 13. Reversibility of Epigenetic Modification Patterns
Chapter 14. Epigenetic Predisposition to Disease and Imprinting-Based Disorders
Chapter 15. Epigenetics of Memory, Neurodegeneration, and Mental Health
Chapter 16. Epigenetics of Cancer