ESSENTIALS OF STEM CELL BIOLOGY. 3RD EDITION

• Part I: Introduction to Stem Cells
Chapter 1. Why Stem Cell Research? Advances in the Field
Chapter 2. ‘Stemness’: Definitions, Criteria, and Standards
Chapter 3. Pluripotent Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges
Chapter 4. Embryonic Stem Cells in Perspective
Chapter 5. The Development of Epithelial Stem Cell Concepts
• Part II: Basic Biology and Mechanisms
Chapter 6. Stem Cell Niches
Chapter 7. Mechanisms of Stem Cell Self-Renewal
Chapter 8. Cell Cycle Regulators in Stem Cells
Chapter 9. How Cells Change Their Phenotype
• Part III: Tissue and Organ Development
Chapter 10. Differentiation in Early Development
Chapter 11. Stem Cells Derived from Amniotic Fluid
Chapter 12. Stem and Progenitor Cells Isolated from Cord Blood
Chapter 13. The Nervous System
Chapter 14. Sensory Epithelium of the Eye and Ear
Chapter 15. Epithelial Skin Stem Cells
Chapter 16. Hematopoietic Stem Cells
Chapter 17. Peripheral Blood Stem Cells
Chapter 18. Multipotent Adult Progenitor Cells
Chapter 19. Mesenchymal Stem Cells
Chapter 20. Skeletal Muscle Stem Cells
Chapter 21. Stem Cells and the Regenerating Heart
Chapter 22. Cell Lineages and Stem Cells in the Embryonic Kidney
Chapter 23. Adult Liver Stem Cells
Chapter 24. Pancreatic Stem Cells
Chapter 25. Stem Cells in the Gastrointestinal Tract
• Part IV: Methods
Chapter 26. Induced Pluripotent Stem Cells
Chapter 27. Embryonic Stem Cells: Derivation and Properties
Chapter 28. Isolation and Maintenance of Murine Embryonic Stem Cells
Chapter 29. Approaches for Derivation and Maintenance of Human Embryonic Stem Cells: Detailed Procedures and Alternatives
Chapter 30. Derivation and Differentiation of Human Embryonic Germ Cells
Chapter 31. Genomic Reprogramming
• Part V: Applications
Chapter 32. Neural Stem Cells – Therapeutic Applications in Neurodegenerative Diseases
Chapter 33. Adult Progenitor Cells as a Potential Treatment for Diabetes
Chapter 34. Burns and Skin Ulcers
Chapter 35. Stem Cells and Heart Disease
Chapter 36. Stem Cells for the Treatment of Muscular Dystrophy
Chapter 37. Cell Therapy for Liver Disease: From Hepatocytes to Stem Cells
Chapter 38. Orthopedic Applications of Stem Cells
Chapter 39. Embryonic Stem Cells in Tissue Engineering
• Part VI: Regulation and Ethics
Chapter 40. Ethical Considerations
Chapter 41. Overview of the FDA Regulatory Process
Chapter 42. It’s Not about Curiosity, It’s about Cures: Stem Cell Research – People Help Drive Progress
Glossary
Index

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world’s experts of the latest research information about specific organ systems. From basic biology/mechanisms, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered.

Features:
• Contributions by Nobel Laureates and leading international investigators
• Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough
• Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate
• Presented in full color with a glossary, highlighted terms, and bibliographic entries replacing references

Authors
• Robert Lanza, Advanced Cell Technology, MA, USA.
• Anthony Atala, Department of Urology, Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA