1 Polyomaviridae 1
James A. DeCaprio • Michael J. Imperiale •
Hans H. Hirsch
2 Papillomaviridae: The Viruses
and Their Replication 45
Alison A. McBride • Peter M. Howley
3 Papillomaviruses 68
John T. Schiller • Douglas R. Lowy
4 Adenoviridae: The Viruses
and Their Replication 98
5 Adenoviruses 129
Thomas Lion • William S. M. Wold
6 Parvoviridae 172
Colin R. Parrish
7 Circoviridae and Anelloviridae 197
Xiang-Jin Meng • Yao-Wei Huang
8 The Family Herpesviridae:
A Brief Introduction 212
Laurie T. Krug • Philip E. Pellett
9 Herpes Simplex Viruses:
Mechanisms of Lytic and
Latent Infection 235
David M. Knipe • Ekaterina E. Heldwein •
Ian J. Mohr • Catherine N. Sodroski
10 Herpes Simplex Viruses: Pathogenesis
and Clinical Insights 297
Richard J. Whitley • Christine Johnston
11 Epstein-Barr Virus 324
Benjamin E. Gewurz • Richard M. Longnecker •
Jeffrey I. Cohen
12 Cytomegalovirus 389
Felicia Goodrum • William Britt • Edward S. Mocarski
13 Varicella–Zoster Virus 445
Ann M. Arvin • Allison Abendroth
14 Human Herpesviruses 6A, 6B,
and 7 489
Yasuko Mori • Danielle M. Zerr • Louis Flamand •
Philip E. Pellett
15 Kaposi’s Sarcoma Herpesvirus 513
Blossom Damania • Ethel Cesarman
16 Poxviridae: The Viruses and
Their Replication 573
Bernard Moss • Geoffrey L. Smith
17 Poxviruses 614
Panayampalli S. Satheshkumar • Inger K. Damon
18 Hepadnaviridae 641
Christoph Seeger • Fabien Zoulim • William S. Mason
19 Hepatitis D (Delta) Virus 683
Camille Sureau • Paul Dény
20 Mimiviridae 704
Matthias G. Fischer
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: DNA Viruses, Seventh Edition covers the latest information on DNA viruses, how they cause disease, including cancer, how they persist in the body in a latent form, reactivate and spread, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field.
Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
• Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis.
• Covers viruses that cause human cancer such as human papillomaviruses (HPV), Epstein Barr Virus, the Merkel Cell Polyomavirus and hepatitis B virus, and viruses like the herpesviruses that persist in a latent form and can reactivate and cause acute and/or chronic disease.
• Features more than 400 full-color illustrations, including key figures for use as lecture slides.
• Provides quick, flexible access to current information both in print and in an improved eBook format.
• Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency and viruses as tools for gene therapy and vectors for vaccination.
New and forthcoming Field’s Virology volumes, available in print and eBook format:
• Emerging Viruses
• DNA Viruses
• RNA Viruses
• Fundamental Viruses
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