FUNCTIONAL IMAGING IN ONCOLOGY, VOL. 1: BIOPHYSICAL BASIS AND TECHNICAL APPROACHES

· Easy-to-read manual on new functional imaging techniques in oncology
· Explains current clinical applications and outlines future avenues
· Includes numerous high-quality illustrations to highlight the major teaching points
In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This well-illustrated two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including preclinical and clinical imaging techniques, based on US, CT, MRI, PET and hybrid modalities. This first volume explains the biophysical basis for these functional imaging techniques and describes the techniques themselves. Detailed information is provided on the imaging of cancer hallmarks, including angiogenesis, tumor metabolism, and hypoxia. The techniques and their roles are then discussed individually, covering the full range of modalities in clinical use as well as new molecular and functional techniques. The value of a multiparametric approach is also carefully considered.

Table of contents (23 chapters)
1.Cancer Biology: What’s Important for Imaging
2.Imaging Biomarkers and Surrogate Endpoints in Oncology Clinical Trials
3.Role of Molecular Imaging in the Era of Personalized Medicine: A Review
4.Radiotherapy and Imaging
5.New Therapies and Functional-Molecular Imaging
6.Medical Image Computing for Oncology: Review and Clinical Examples
7.Imaging Angiogenesis
8.Imaging of Tumor Metabolism: MR Spectroscopy
9.Imaging of Tumour Metabolism: 18-FDG PET
10.Imaging of Tumor Metabolism: PET with Other Metabolites
11.Current Clinical Imaging of Hypoxia with PET and Future Perspectives
12.MRI Hypoxia Measurements
13.Overview of Functional MR, CT, and US Imaging Techniques in Clinical Use
14.Diffusion-Weighted MR Imaging
15.Perfusion CT: Principles, Technical Aspects and Applications in Oncology
16.Perfusion Imaging by Magnetic Resonance
17.DCE-US: Evaluation of Angiogenesis
18.Spectroscopy of Cancer
19.Hybrid Imaging: PET-CT and PET-MRI
20.Dual-Energy and Spectral Energy Computed Tomography: Oncological Body Applications in Clinical Use
21.US Elastography: Applications in Tumors
22.New Molecular and Functional Imaging Techniques
23.Multiparametric Imaging