GENE REGULATION AND THERAPEUTICS FOR CANCER

GENE REGULATION AND THERAPEUTICS FOR CANCER

Editorial:
ROUTLEDGE
Año de edición:
Materia
Genética
ISBN:
978-1-138-71242-3
Páginas:
326
N. de edición:
1
Idioma:
Inglés
Ilustraciones:
20
Disponibilidad:
Disponible en 2-3 semanas

Descuento:

-5%

Antes:

182,00 €

Despues:

172,90 €

• Programmed Death 1 Receptor (PD-1)-mediated Immunomodulatory Effects in Pancreatic Cancer
• Nuclear Factor Kappa-B: Bridging Inflammation and Cancer
• The S100A7/8/9 Proteins: Novel Biomarker and Therapeutic Targets for Solid Tumor Stroma
• Nuclear Receptor Coactivators: Mechanism and Therapeutic Targeting In Cancer
• Liquid Biopsies for Pancreatic Cancer: A Step Towards Early Detection
• Targeting Subgroup-specific Cancer Epitopes for Effective Treatment of Pediatric Medulloblastoma
• Aberrant Methylation of UC Promoters in Human Pancreatic Ductal Carcinomas
• Receptor Tyrosine Kinase Signaling Pathways as a Goldmine for Targeted Therapy in Head and Neck Cancers
• Molecular Drivers in Lung Adenocarcinoma: Therapeutic Implications
• Molecular Mediator of Prostate Cancer Progression and Its Implication in Therapy
• Therapeutic Options for Prostate Cancer: A Contemporary Update
• Regulation and Targeting of MUCINS in Pancreatic Cancer
• Targeted Therapy for Cancer Stem Cells

Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.