GOLDFRANK´S TOXICOLOGIC EMERGENCIES. 11TH EDITION

1. Historical Principles and Perspectives
2. Toxicologic Misfortunes and Catastrophes in History
• PART A. THE GENERAL APPROACH TO THE PATIENT
3. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
4. Principles of Managing the Acutely Poisoned or Overdosed Patient
SC1. PRINCIPLES OF ANTIDOTE STOCKING
5. Decontamination Principles: Prevention of Gastrointestinal Absorption
SC2. DECONTAMINATION PRINCIPLES: PREVENTION OF DERMAL, INHALATIONAL AND OCULAR ABSORPTION
A1. ACTIVATED CHARCOAL
A2. WHOLE-BOWEL IRRIGATION AND OTHER INTESTINAL EVACUANTS
6. Principles and Techniques Applied to Enhance Elimination
7. Laboratory Principles
8. Principles of Diagnostic Imaging
9. Pharmacokinetic and Toxicokinetic Principles
• PART B. THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY
SECTION I BIOCHEMICAL AND MOLECULAR CONCEPTS
10. Chemical Principles
11. Biochemical and Metabolic Principles
12. Fluid, Electrolyte, and Acid?Base Principles
13. Neurotransmitters and Neuromodulators
14. Withdrawal Principles
SECTION II PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS
15. Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles
16. Cardiologic Principles II: Hemodynamics
17. Dermatologic Principles
SC3. TRANSDERMAL TOXICOLOGY
18. Gastrointestinal Principles
19. Genitourinary Principles
20. Hematologic Principles
21. Hepatic Principles
22. Neurologic Principles
23. Oncologic Principles
24. Ophthalmic Principles
25. Otolaryngologic Principles
26. Psychiatric Principles
27. Renal Principles
28. Respiratory Principles
29. Thermoregulatory Principles
SECTION III SPECIAL POPULATIONS
30. Reproductive and Perinatal Principles
31. Pediatric Principles
32. Geriatric Principles
• PART C. THE CLINICAL BASIS OF MEDICAL TOXICOLOGY
SECTION I. A. ANALGESICS AND ANTIINFLAMMATORY MEDICATIONS
CASE STUDY 1
33. Acetaminophen
A3. N-ACETYLCYSTEINE
34. Colchicine, Podophyllin, and the Vinca Alkaloids
35. Nonsteroidal Antiinflammatory Drugs
36. Opioids
A4. OPIOID ANTAGONISTS
SC4. INTERNAL CONCEALMENT OF XENOBIOTICS
SC5. HARM REDUCTION FOR OPIOID OVERDOSE
37. Salicylates
A5. SODIUM BICARBONATE
B. FOOD, DIET, AND NUTRITION
CASE STUDY 2
38. Botulism
A6. BOTULINUM ANTITOXIN
39. Food Poisoning
40. Dieting Xenobiotics and Regimens
41. Athletic Performance Enhancers
42. Essential Oils
43. Herbal Preparations
44. Vitamins
45. Iron
A7. DEFEROXAMINE
C. PHARMACEUTICALS
CASE STUDY 3
46. Pharmaceutical Additives
47. Antidiabetics and Hypoglycemics/Antiglycemics
A8. DEXTROSE (d-Glucose)
A9. OCTREOTIDE
48. Antiepileptics
A10. L-carnitine
49. Antihistamines and Decongestants
A11. PHYSOSTIGMINE SALICYLATE

The best edition yet of the landmark text in medical toxicology

A Doody’s Core Title for 2019!

Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins.
Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations.
The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis.

New to this Edition:
• Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes
• New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies
• New content on toxicogenomics explores its increasingly important role in predictive toxicology
• Chapter-ending bulleted summaries of key points
• Updated coverage of synthetics such as “K2”
• Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools