HANDBOOK OF CANNABIS AND RELATED PATHOLOGIES.

• Part I: Setting the Scene, Botanical, General and International Aspects
Chapter 1: The Cannabis Plant: Botanical Aspects
Chapter 2: The Biosynthesis of Cannabinoids
Chapter 3: Increasing Plant Concentrations of THC and Implications on Health Related Disorders
Chapter 4: Age as a Predictor of Cannabis Use
Chapter 5: Lifetime Cannabis Use and Cognition in Psychosis Spectrum Disorders
Chapter 6: A Profile of Synthetic Cannabinoid Users
Chapter 7: Dual Disorders in Cannabis Misuse
Chapter 8: Cannabis Use and Cognitive Function
Chapter 9: Cannabis, Migration, and Psychosis Onset
Chapter 10: The Global Epidemiology and Disease Burden of Cannabis Use and Dependence
Chapter 11: International Aspects of Cannabis Use and Misuse: the Australian Perspective
Chapter 12: International Aspects of Cannabis Use and Misuse: Egypt
Chapter 13: Cannabis Body Packing: A Caribbean Perspective
Chapter e1: Tetrahydrocannabinol Concentration and Genetic Characterization of Cannabis
• Part II: Personal, Social and Community Aspects of Cannabis use
Chapter 14: Gender Differences in Cannabis Use Disorders
Chapter 15: The Role of Age in the Onset and Further Development of Cannabis Use Disorders
Chapter 16: Effects of Cannabis Use on Neurocognition in Adolescents and Emerging Adults
Chapter 17: Correlates and Consequences of Prenatal Cannabis Exposure (PCE): Identifying and Characterizing Vulnerable Maternal Populations and Determining Outcomes for Exposed Offspring
Chapter 18: Cannabis and Clubbing: Relevance of Cannabis and Polydrug Use in the Clubbing Culture Today
Chapter 19: Cannabis and Sexual Behavior
Chapter 20: Friendships and Cannabis Use
Chapter 21: Students’ Knowledge of Cannabis
Chapter 22: Childhood Trauma and Cannabis: Risk Factors in Severe Mental Disorders?
Chapter 23: Parent’s Influence on Children’s Cannabis Use
Chapter 24: Cannabis Users and Premorbid Intellectual Quotient
Chapter 25: Cannabis and Traffic Accidents
Chapter e2: Cannabis Use in Youth Subcultures
• Part III: Cannabis, Behavior, Psychopathology and Neuropathology
Chapter 26: Drug-Related Pictures, Attentional Bias, and Cannabis Use
Chapter 27: Cannabis Use and First-Episode Psychosis Patients (FEP)
Chapter 28: Cannabis, Associative Memory, fMRI, and the Implicit Association Test
Chapter 29: Stress Response in Cannabis Users and Psychosis
Chapter 30: Motivation in Chronic Cannabis Use
Chapter 31: Cannabis Use and Its Association to Mental Illness: A Focus on Mood and Anxiety Disorders
Chapter 32: Cannabis Use and Well-Being
Chapter 33: Craving and Cannabis: A Potential Paradox
Chapter 34: Delta-9-Tetrahydrocannabinol and Catalepsy-Like Immobilization
Chapter 35: The Interactive Nature of Cannabis and Schizophrenia Risk Genes
Chapter 36: Neuroimaging Findings in Adolescent Cannabis Use and Early Phase Psychosis
Chapter 37: Cannabis Smoking in Adult Schizophrenia: A Cognitive and Functional Magnetic Resonance Imaging Perspective
Chapter 38: The Long-Lasting Effects of Cannabis Use on Movement and Brain Regions that Control Movement
Chapter 39: Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies
Chapter 40: Chronic Cannabis Use and Axonal Fiber Connectivity
Chapter 41: Microglial Activation and Cannabis Exposure
Chapter 42: Cannabis and Psychosis: Correlation, Causality, and Consequences
Chapter 43: Cannabis Use in Bipolar Disorder
Chapter 44: Cannabis Use in Epilepsy—Risks and Benefits
Chapter 45: Cannabis, Cannabinoids, and Visceral Pain
Chapter 46: Cannabis and Postoperative Analgesia
Chapter e3: Aggressive Behavior and Cannabis Use
Chapter e4: COMT Genotypes, Cannabis Use, and Psychosis: Gene-Environment Interaction Evidence from Human Populations, and Its Methodological Concerns
Chapter e5: Neuroimaging and Genetics of the Acute and Chronic Effects of Cannabis
Chapter e6: Gray Matter, Lateral Ventricle Volumes, and Executive Functioning in Cannabis Users with First-Episode Psychosis
Chapter e7: Cannabis Use and Attention-Deficit/Hyperactivity Disorder: Potential Moderators
• Part IV: Cannabis, Organs, Tissues and Non-cns Aspects
Chapter 47: Chronic Cannabis Abuse and Thyroid Function
Chapter 48: Cannabis Hyperemesis Syndrome
Chapter 49: Cannabis and Cannabinoids and the Effects on Gastrointestinal Function: An Overview
Chapter 50: Cardiovascular Effects of Cannabis Usage
Chapter 51: Cannabis and Stroke
Chapter 52: Cannabis Smoking and the Lung
Chapter 53: Cannabis and Hepatic Injury
Chapter 54: Cannabis Allergy: More Than a Bad Trip
Chapter 55: Marijuana and Breastfeeding
Chapter 56: Hypocretins/Orexins and Addiction: Role in Cannabis Dependence
Chapter 57: Regulatory Role of Cannabinoids for Skin Barrier Functions and Cutaneous Inflammation
Chapter e8: Cannabis and Oral Health: Deleterious Effects on Periodontitis and Dental Implants
Chapter e9: Does Cannabis Use Increase the Risk of Developing Cancer in Humans?
Chapter e10: Cannabis and the Use of Amphetamine-Like Substances
• Part V: Pharmacology and Cellular Activities of Cannabinoids and Endocannabinoids
Chapter 58: Cannabinoids and the Cannabinoid Receptors: An Overview
Chapter 59: Signaling and Regulation of the Cannabinoid CB1 Receptor
Chapter 60: Allosteric Modulation of the Cannabinoid CB1 Receptor
Chapter 61: Polymorphisms of the CB2 Cannabinoid Receptor
Chapter 62: Chemistry of Cannabinoid Receptor Agonists
Chapter 63: The Endocannabinoid System as a Target for New Antiseizure Drugs
Chapter 64: Pharmacological Aspects of Anandamide and 2-Arachidonoyglycerol as Bioactive Lipids
Chapter 65: Pharmacological Aspects of NMDA Receptors, mGluR5, and Endocannabinoids
Chapter 66: Peripheral CB1 Receptors and Ghrelin in Feeding Regulation: Pharmacological Implications
Chapter 67: Pharmacological Aspects of Novel Antiobesity Agents Related to Cannabinoids
Chapter 68: Cannabinoid Reward and Dependence: Focus on the Main Psychoactive Ingredients of Marijuana in Preclinical Studies
Chapter 69: Peroxisome Proliferator Activated Receptors and Cannabinoids
Chapter 70: The Protein–Protein Interactions of Cannabinoid Receptor Interacting Protein 1a (CRIP1a) and Cannabinoid 1 Receptor: The Molecular Mechanism Study Through an Integrated Molecular Modeling Approach
Chapter 71: Synthetic Cannabinoids: a Summary of Selected Phenomena With Respect to Behavioral Pharmacology and Abuse Liability
Chapter e11: Cannabinoid Signaling in Glioma Cells and Therapeutic implications
• Part VI: Effects of Specific Natural and Synthetic Cannabinoids
Chapter 72: The Role of 5-HT1A Receptor, and Nausea and Vomiting Relief by Cannabidiol (CBD), Cannabidiolic Acid (CBDA), and Cannabigerol (CBG)
Chapter 73: Genetic and Molecular Aspects of Addiction with Tetrahydrocannabinol
Chapter 74: Effects of ?9-Tetrahydrocannabinol in Human Breast Cancer
Chapter 75: ?9-THC and COX-2 Signaling
Chapter 76: Cannabinoids and the Addictive Effects of Nicotine
Chapter 77: Cannabinoid Regulation of Intraocular Pressure: Human and Animal Studies, Cellular and Molecular Targets
Chapter 78: Ocular Delivery of Tetrahydrocannabinol
Chapter 79: The Role of ?-Aminobutyric Acid in the Interoceptive Effects of Oral ?9-Tetrahydrocannabinol in Humans
Chapter 80: The Role of ?9-Tetrahydrocannabinol in Diabetes Mellitus
Chapter 81: Cannabidiol: An Overview of its Antipsychotic Properties
Chapter 82: Cannabidiol for the Treatment of Epilepsy: An Overview of Possible Mechanisms of Action and Preclinical and Human Studies
Chapter 83: Cannabidiol and Neuroprotection: Evidence from Preclinical Studies
Chapter 84: Cannabinoids as Potent Inhibitors of Human CYP1 Enzymes
Chapter 85: The Synthetic Analog of ?9-Tetrahydrocannabinol (THC): Nabilone. Pharmacology and Clinical Application
Chapter 86: Synthetic Cannabinoids in Dementia
Chapter 87: Synthetic Cannabinoid Receptor Agonists (Spice) as New Recreational Psychoactive Substances
Chapter 88: Accidents and Synthetic Cannabinoids in Blood of Drivers
Chapter e12: Cannabidiol as an Antioxidant
Chapter e13: The Anxiolytic Effects of Cannabidiol (CBD)
Chapter e14: New Ethological and Morphological Perspectives for the Investigation of Panicolytic-Like Effects of Cannabidiol
Chapter e15: Spice Use Among United States Military Personnel
• Part VII: Medicinal Cannabis use
Chapter 89: Cannabis and Synthetic Cannabinoids for Cancer Patients: Multiple Palliative Indications Together With Promising Laboratory Antineoplastic Effects
Chapter 90: The Use of Medical Marijuana in the Treatment of Psychiatric Disorders
Chapter 91: Beneficial Effects of Cannabis and Related Compounds on Sleep
Chapter 92: Cannabinoid-Based Medicines for the Treatment of Gilles de la Tourette Syndrome
Chapter 93: Cannabidiol and Multiple Sclerosis
Chapter 94: Cannabinoids and Their Effects on Painful Neuropathy
Chapter 95: Cannabis for Basal Ganglia Disorders (Parkinson Disease and Huntington Disease)
Chapter 96: Medical Cannabis for the Treatment of Inflammatory Bowel Disease
Chapter 97: Cannabidiol for the Treatment of Drug Use Disorders
Chapter 98: Cannabinoids and Effects on the Gastrointestinal Tract: A Focus on Motility
Chapter 99: Potential Medical Uses of Cannabigerol: A Brief Overview
Chapter e16: Cannabis Use in Fibromyalgia
• Part VIII: Screening, Diagnosis, and Treatment
Chapter 100: The Cannabis Abuse Screening Test (CAST) and Its Applications
Chapter 101: Screening of Synthetic Cannabinoids
Chapter 102: On-Site Drug Testing for Cannabis
Chapter 103: Cannabinoids in Oral Fluid: Identification and Interpretation of Analytical Results
Chapter 104: Cannabinoids in Exhaled Breath
Chapter 105: Barriers to Treatment Seeking for Cannabis Dependence
Chapter 106: Pharmacotherapies for Cannabis Use Disorders
Chapter 107: Self-Initiated Cannabis Use Cessation in Adolescents and Emerging Adults
Chapter 108: Treating Cannabis-Dependent Adolescents with Family Therapy: The case of Multidimensional Family Therapy
Chapter 109: Cognitive Behavioral Therapy in Cannabis Use Disorder
Chapter 110: The Cannabis Withdrawal Syndrome— Symptoms and Time Course
Chapter 111: School-Based Cannabis Prevention Programs
Chapter 112: The CapOpus Trial for Cannabis Use Disorders
Chapter 113: Treating Cannabis Use Disorders Through Technology-Assisted Interventions: the Telephone and Internet
Chapter 114: Reducing Cannabis Use With a Real-Time Intervention Using Mobile Technology
Chapter e17: Short Instruments to Screen for “Problematic” Cannabis Use in General Population Surveys
Chapter e18: Self-report of Cannabis Use
Chapter e19: CANDIS Program: Modular Treatment of Cannabis Use Disorders
Chapter e20: Engaging Cannabis Users in Treatment
• Cannabis Neuropathology Resources and Recommended Reading
• Index

Features:
• Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points
• Presents illustrations with at least six figures, tables, and diagrams per chapter
• Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment
• Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse

Author
Victor R. Preedy, Department of Dietetics, King's College London, UK