HEALTH IMPACTS OF DEVELOPMENTAL EXPOSURE TO ENVIRONMENTAL CHEMICALS

• Part 1 Introduction
1 Impacts of developmental exposure to environmental chemicals on human health with global perspectives
• Part 2 Adverse health effects on human developing organs caused by environmental chemicals-the role that chemicals might play
2 Environmental exposures and adverse pregnancy-related outcomes
3 Effects of Environmental Chemical Exposure on Birth Defects (Except Cryptorchidism and Hypospadias)
4 Cryptorchidism and hypospadias
5 Endocrine-distributing chemicals and reproductive function
6 Thyroid hormone system and development
7 Neurodevelopment and Neurobehavioral disorders in relation to developmental exposures
8 Immunotoxicity: Impacts and research approaches
9 Long-Term Implications of Developmental Programming and Obesity
• Part 3 Impact of Environmental Chemical Hazards on human development
10 Impact of Air Pollution Hazards on Human Development
11 Mercury, Lead, Manganese and Hazardous Metals
12 Environmental Pollution and Recent Data on Asian Children’s Health in Relation to Pre- and Early Post-natal Exposure to Persistent Organic Pollutants, Including PCBs, PCDD/PCDFs, and Organochlorine Pesticides
13 Effects of Developmental Exposure to Perfluoroalkyl Substances on Health Outcomes in Pregnant Women and Offspring
14 Brominated flame retardants (BFRs)
15 Exposure to phthalate acid esters and the its health effects
16 Bisphenols and alkylphenols
• Part 4 Important aspects of research for prevention and strategy
17 Adverse Outcome Pathways for Developmental Toxicity
18 Exposomics-The Exposome in Early Life
19 Gene-Environment Interactions to Detect Adverse Health Effects on the Next Generation
20 Epigenetics – Strategies for Prevention Research
21 From research to intervention
• Part 5 Closing
22Further direction of research and policy making of environment and children's health.

This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects.
Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.

Features
• Presents concise and cutting-edge studies on how exposure to environmental chemicals can affect human health and development, including the burgeoning DOHaD concept
• Provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research
• Puts forward ideas on how to bridge the gap between research evidence and policymaking