HOFFBRAND'S ESSENTIAL HAEMATOLOGY, 7TH EDITION

The definitive haematology textbook of choice for medical students

Hoffbrand’s Essential Haematology has built a reputation as the flagship haematology textbook for both students and junior doctors, providing an authoritative introduction to the subject.

Now in its 7th edition, this classic text provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, treatment of blood and bone marrow disorders, in its concise and user-friendly style.

Hoffbrand’s Essential Haematology outlines the basic principles of clinical and laboratory haematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes. It is an indispensable resource for students and trainees and an essential read for all specialists who are interested in updating their knowledge.

Hoffbrand’s Essential Haematology:
- Provides up-to-date knowledge of the pathogenesis, clinical and laboratory features and treatment of all blood disorders
- Features detailed information on the new genetics of leukaemia and lymphoma
- Includes a new chapter on thrombosis, focussing on the new oral anticoagulants
- Is beautifully presented, with over 300 colour illustrations
- Comprehensively covers both theory and treatment regimes
- Includes a companion website at www.wileyessential.com/haematology featuring all the figures and tables from the book, and over 300 interactive multiple choice questions

Table of Contents
Preface to the Seventh Edition vi
Preface to the First Edition vii
How to use your textbook viii
About the companion website x
1 Haemopoiesis 1
2 Erythropoiesis and general aspects of anaemia 11
3 Hypochromic anaemias 27
4 Iron overload 41
5 Megaloblastic anaemias and other macrocytic anaemias 48
6 Haemolytic anaemias 60
7 Genetic disorders of haemoglobin 72
8 The white cells 1: granulocytes, monocytes and their benign disorders 87
9 The white cells 2: lymphocytes and their benign disorders 102
10 The spleen 116
11 The aetiology and genetics of haematological malignancies 122
12 Management of haematological malignancy 135
13 Acute myeloid leukaemia 145
14 Chronic myeloid leukaemia 156
15 Myeloproliferative disease 165
16 Myelodysplasia 177
17 Acute lymphoblastic leukaemia 186
18 The chronic lymphoid leukaemias 197
19 Hodgkin lymphoma 205
20 Non-Hodgkin lymphoma 213
21 Multiple myeloma and related disorders 228
22 Aplastic anaemia and bone marrow failure 242
23 Stem cell transplantation 250
24 Platelets, blood coagulation and haemostasis 264
25 Bleeding disorders caused by vascular and platelet abnormalities 278
26 Coagulation disorders 290
27 Thrombosis 1: pathogenesis and diagnosis 302
28 Thombosis 2: treatment 311
29 Haematological changes in systemic disease 321
30 Blood transfusion 333
31 Pregnancy and neonatal haematology 346
Appendix: World Health Organization classification of tumours of the haematopoietic and lymphoid tissues 352
Index 357