HORIZONS IN CANCER RESEARCH. VOLUME 77

Preface
• Chapter 1. Advances in Diagnosis of Leukemia by Aptamer Based Biosensors
(Lenka Babelova, Cyril Slaby, Jozef Bizik, Martin Razus, Andreas Ebner and Tibor Hianik, Institute of Animal Biochemistry and Genetics, Center of Biosciences SAS, Bratislava, Slovakia, and others)
• Chapter 2. Melanoma Cell Lines as a Model for High-Throughput Drug Screening
(Juliana Alves do Vale, Graziela Domingues de Almeida Lima, Alisson Andrade Almeida, Róbson Ricardo Teixeira and Mariana Machado-Neves, General Biology Department, Federal University of Viçosa, Viçosa, Minas Gerais State, Brazil, and others)
• Chapter 3. Current Practices and Advances in Diagnosis and Management of Gastroenteropancreatic Carcinoid Tumors in Children
(Konstantina Dimopoulou, Anastasia Dimopoulou, Emmanouil Iakomidis and Nikolaos Zavras, Department of Gastroenterology, General Hospital “Hippokration,” Athens, Greece, and others)
• Chapter 4. Traditional Formosan Medicine on Cancer Therapy in 21st Century
(Ying-Ling Chen and Mark C. Hou, School of Chinese medicine, China Medical University, Taichung, Taiwan, and others)
• Chapter 5. Structural Bioinformatics Approach for the Molecular Models of mir-135b and Its Silencer as Triple Negative Breast Cancer (TNBC) Biomarkers
(Margareta Deidre Valeska and Arli Aditya Parikesit, Department of Bioinformatics, School of Life Sciences, Indonesia International Institute for Life Sciences, Jakarta, Indonesia)
Index

In this compilation, an overview of recent achievements in clinical and biosensor technology in the diagnosis of acute lymphoblastic leukemia is provided. Various aptasensors such as optical, electrochemical and mass-sensitive are presented along with a novel approach for the recognition of cancer markers by molecular imaging methods based on atomic force microscopy, single molecule force spectroscopy and topography and recognition imaging.

The authors review the strategies used to screen potential antimelanoma drugs, especially those involved in evaluating drugs in cancer cell lines, in vitro and in vivo, as well as in silico tests used for drug selection.

Following this, a study is presented focusing on gastroenteropancreatic carcinoids tumors, rare slow-growing lesions that derive from primitive stem cells of the gut.

The authors explore the influence of Traditional Formosan medicine on cancer therapy through a literature review and expert opinion. Three clinical experiences of using Formosan medicine for cancer therapy are discussed: acupuncture, herb, and Formosan medicine tongue diagnosis.

The concluding research utilizes the extensive pipelines of the Vienna RNA package for 2D RNA structure prediction, and the result exposes a satisfactory illustration and narration of the predicted RNA structures.