HORMONAL AND GENETIC BASIS OF SEXUAL DIFFERENTIATION DISORDERS AND HOT TOPICS IN ENDOCRINOLOGY: PROCEEDINGS OF THE 2ND WORLD CONFERENCE

1. Congenital Adrenal Hyperplasia Owing to 17a-Hydroxylase/17,20 Lyase and P450 Oxidoreductase Deficiencies
2. Congenital Adrenal Hyperplasia Owing to 11ß-Hydroxylase Deficiency
3. 46,XY DSD due to 17ß-HSD3 Deficiency and 5a-Reductase Type 2 Deficiency
4. Studies of a Cohort of 46,XY with DSD Including Steroid Biosynthesis Deficiencies
5. Aromatase Deficiency and Its Consequences
6. Gonadotropin-Regulated Testicular Helicase (GRTH/DDX25): A Master Post-transcriptional Regulator of Spermatogenesis
7. Long Range Outcome of Prenatal Treatment
8. Novel Non-invasive Prenatal Diagnosis as Related to Congenital Adrenal Hyperplasia
9. Medical Treatment of Classic and Nonclassic Congenital Adrenal Hyperplasia
10. Apparent Mineralocorticoid Excess – Update
11. Clitoroplasty in Congenital Adrenal Hyperplasia: Description of Technique
12. Genitoplasty/Vaginoplasty
13. Insights into the Aetiology of Ovotesticular DSD from Studies of Mouse Ovotestes
14. 46,XY Disorders of Sex Development (46,XY DSD) due to Androgen Receptor Defects: Androgen Insensitivity Syndrome
15. Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: A High Content Analysis Approach Leading to Personalized Medicine
16. Phenotypic Variation of SF1 Gene Mutations
17. Transsexualism (“Gender Identity Disorder”) – A CNS-Limited Form of Intersexuality?
18. Biology and Genetics of Anti-Müllerian Hormone
19. Genetic Mechanisms Underlying 46,XY DSD with Gonadal Dysgenesis
20. Genetic Disorders of Sex Differentiation
21. The Clinical Spectrum and Treatment of Ovotesticular Disorder of Sexual Development
22. The Genetics of Ovotesticular Disorders of Sex Development
23. Growth Hormone Treatment in Children with Congenital Adrenal Hyperplasia
24. Genetic Modifications of Corticosteroid Receptors in Hypertension
25. Angiotensin AT2 Receptors: Control of Renal Sodium Excretion and Blood Pressure
26. The Pituitary-Bone Axis
27. Genetic Impact of Both Sex Hormones in Male-Typical Behaviors
28. MAMLD1 (Mastermind-Like Domain Containing 1) Homozygous Gain-of-Function Missense Mutation Causing 46,XX Disorder of Sex Development in a Virilized Female
29. Atypical Presentation and Novel StAR Protein Gene Mutation in a 46,XY Female with Lipoid Congenital Adrenal Hyperplasia
30. Patient-Centered Care: Caring for Families Affected by Disorders of Sex Development
31. Assessing Health-Related Quality of Life in Disorders of Sex Development: Phase I – Item Generation
32. Leydig Cell Hypoplasia due to Inactivating Luteinizing Hormone/Chorionic Gonadotropin Receptor Gene Mutation Presenting as a 46,XY DSD
33. Inguinal Hernia in a Phenotypic Female Infant May Reveal a 46XY Sex Reversal, Supported by the Identification of a Novel SF1 Gene Mutation
34. University of Michigan Disorders of Sex Development (DSD) Research and Quality Improvement Symposium
35. The Challenge of Mistaken Sex Assignment in an 11-Year-Old with Virilizing CAH
36. Report of Fertility in a Woman with a Predominantly 46,XY Karyotype in a Family with Multiple Disorders of Sexual Development

Proceedings of the 2nd World Conference – Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology. The meeting took place at The Eden Roc Hotel in Miami Beach, Florida, 1/15/10 – 1/17-10. Endocrinology and more specifically, the area of sexual differentiation disorders is an evolving field of medicine. The diagnosis and treatment of Disorders of Sex Development (DSD) is multi-faceted.

Features
• Looks at the evolving field of endocrinology and sexual differentiation disorders
• Highlights the best science and medicine on disorders of current, important topics in endocrinology and genetics
• Covers current topics in endocrinology including skeletal biology and epigenetics