1. Generic Aspects of Hybrid Imaging
• Hybrid Imaging and Healthcare EconomicsPages 3-13
• Industry Perspective on Hybrid Cardiac ImagingPages 15-23
• Global and Regional Peculiarities: The IAEA PerspectivePages 25-43
• Perfusion, Calcium Scoring, and CTAPages 47-58
• Hybrid Imaging of the Autonomic Cardiac Nervous SystemPages 59-82
• DyssynchronyPages 83-102
• Novel Techniques: Solid-State Detectors, Dose Reduction (SPECT/CT)Pages 103-129
• Myocardial Blood Flow Quantification with PET/CT: ApplicationsPages 133-149
• Hybrid PET-CT Evaluation of Myocardial ViabilityPages 151-164
• Myocardial Inflammation: Focus on Cardiac SarcoidosisPages 165-187
• Novel SPECT and PET Tracers and Myocardial ImagingPages 189-228
• PET/MR: Perfusion and ViabilityPages 231-241
• PET/MRI: “Inflammation”Pages 243-264
• Innovations in Cardiovascular MR and PET-MR Imaging
This clinically oriented book provides an up-to-date review on the various hybrid imaging modalities that may be employed for the purpose of cardiac imaging. After discussion of generic aspects of hybrid imaging, SPECT/CT, PET/CT, and PET/MRI are each considered in depth. In addition, information is provided on upcoming technologies, such as dedicated so-called fast cardiac cameras (CZT detector technology) and novel probes and radiotracers. A wide variety of topics are addressed, including important technological aspects, possible applications, imaging protocols, peculiarities of the available modalities, radiation exposure, and dose reduction. Last but not least, an estimation of the cost efficiency of dedicated and hybrid imaging devices in cardiology is provided and possible scenarios with respect to health care economics are envisioned. Hybrid Cardiac Imaging will be of particular value for nuclear medicine specialists, cardiologists, and radiologists and will also be of interest to medical physicists, medical technicians, and cardiothoracic surgeons.
• Reviews all clinically relevant hybrid imaging modalities: SPECT/CT, PET/CT, and PET/MRI
• Discusses applications, instrumentation, protocols, peculiarities, and economic aspects
• Considers the role of novel imaging probes
• Stephan G. Nekolla, PhD, FESC, is adjunct professor and the director of medical physics at the Department of Nuclear Medicine at Technische Universität München (Germany). Dr. Nekolla’s research fields are design, acquisition and analysis of PET, SPECT, MRI and CT studies, workflow considerations and quantification methods in clinical and pre-clinical studies. His primary focus is the optimal use of non-invasive imaging to understand the mechanism of disease in cardiology and oncology, their detection and therapy assessment. Especially the use of hybrid devices such as SPECT/CT, PET/CT, and PET/MRI their optimal use in cardiac and oncological imaging is of special relevance.
He is the author/co-author of > 260 peer-reviewed publications, book chapters and review articles (Publons H-index: 60, L-1857-2013).
Dr. Nekolla is chair of the working group medical physics of the German Society of Nuclear Medicine, ESMIT representative of the physics committee of the European Society of Nuclear Medicine and member of the ESC/EACVI Nuclear Cardiology and Cardiac CT Section.
As part of the interdisciplinary imaging network at TU München, he is senior affiliated lecturer at the Chair of Computer Aided Medical Procedures & Augmented Reality (CAMPAR), member of the MunichHeartAlliance as well as member of the German Center of Cardiovascular Research (DZHK).
After studying physics at the University of Würzburg, Germany and his diploma thesis at the Institute of Biotechnology, he received his PhD at the Institute of Physics, University of Würzburg, before moving to Munich.
• Christoph Rischpler, MD, is a Consultant at the Clinic of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Germany and holds a professorship for Nuclear Cardiology. He completed his residency at the Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Germany where he focused^110 peer-reviewed publications, book chapters, and review articles and has an h-index of 28.