IMMUNOLOGY. 10TH EDITION

SECTION 1 The Immune System and Innate Immunity
1. Introduction to the Immune System
2. Cells, Tissues and Organs of the Immune System
3. Mechanisms of Innate Immunity
4. Complement
5. Mononuclear Phagocytes in Immune Defence

SECTION 2 Adaptive Immune Responses
6. T-Cell Receptors and Major Histocompatibility Complex Molecules
7. Antigen Presentation
8. Cell-Mediated Cytotoxicity
9. B-Cell Development and the Antibody Response
10. Antibodies
11. Immunological Tolerance
12. Regulation of the Immune Response
13. Immune Responses in Tissues

SECTION 3 Defence Against Infectious Agents
14. Immunity to Viruses
15. Immunity to Bacteria and Fungi
16. Immunity to Protozoa and Worms
17. Vaccination

SECTION 4 Immunodeficiency
18. Primary Immunodeficiencies
19. AIDS, Secondary Immunodeficiency and Immunosuppression

SECTION 5 Immune Responses Against Tissues
20. Autoimmunity and Autoimmune Disease
21. Transplantation and Rejection
22. Immunity to Cancers

SECTION 6 Hypersensitivity
23. Immediate Hypersensitivity (Type I)
24. Hypersensitivity (Type II)
25. Hypersensitivity (Type III)
26. Hypersensitivity (Type IV)

**Selected for 2025 Doody’s Core Titles® in Immunology**

Immunology is highly valued by medical students and medical science students everywhere for demystifying a complex and rapidly developing area of medicine.

The book integrates basic and clinical immunology, providing up-to-date information that links the laboratory with clinical practice. It covers all the core immunology concepts that students need for their coursework, including immunity, immune responses, defence against infectious agents, and hypersensitivity.

The book's structure makes it easy to understand, presenting immunology in the order that aligns with typical teaching methods. Ideal for USMLE and MLA preparation, it comes complete with accompanying online animations, cases studies, and self-assessment.

Features:
• Carefully structured layout - easy to follow and identify high yield information
• Explains the building blocks of the immune system - cells, organs and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context
• More learning opportunities online, including USMLE-style questions and clinical cases – ideal for exam revision and practice
• Animations offer a visual overview of immunological concepts
• An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
New To This Edition:
• More case studies
• Thoroughly updated coverage of:
? Viruses
? Transplantation
? Vaccination
? Immunodeficiencies
? Checkpoint inhibitors
? Anti-malarial vaccines
? Antibody and cell-based therapies

Authors
• David Male, MA, PhD, Professor of Biology, Department of Life Sciences, The Open University, Milton Keynes, UK.
• R. Stokes Peebles, Jr., MD, Professor of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
• Victoria Male, MA, PhD, Sir Henry Dale Fellow, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom