Descuento:
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Despues:
148,19 €1. Overview of Current Cancer Immunotherapy
2. Bacterial Preparations
3. Polysaccharides
4. BCG
5. aß-T Cells
6. NKT Cell-Based Immunotherapy
7. Natural Killer Cells
8. ?d T Cell-Based Cancer Immunotherapy
9. Genetically Engineered T Cells
10. Peptide Vaccine
11. Personalized Peptide Vaccine
12. WT1 Peptide Vaccine for the Treatment of Malignancies: Its Development, Recent Progress, and Future Perspectives
13. Protein Vaccine
14. Dendritic Cell-Based Vaccine for Cancer
15. CpG Motif
16. Pattern Recognition by Dendritic Cells and Its Application to Vaccine Adjuvant for Antitumor Immunotherapy
17. Novel Adjuvants
18. Anti-CTLA-4 Ab
19. Anti-PD-1 and Anti-PD-L1 mAbs
20. Novel Targets of Immune Inhibitory and Stimulatory Co-signals
21. Regulatory T Cells
22. MDSC: Myeloid-Derived Suppressor Cells
23. Immune-Related Response Criteria and Guidance for Clinical Trials
24. Personalized Cancer Immunotherapy: Immune Biomarkers and Combination Immunotherapy
This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted.
With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.
Features
• Summarizes the rationale, present status, and future perspective for cancer immunotherapy
• Provides comprehensive knowledge of the mechanism of cancer immunotherapy
• Enriches the reader’s understanding of personalized clinical application of cancer immunotherapy
Author
Dr. Yoshiyuki Yamaguchi, MD, PhD, Professor, Department of Clinical Oncology, Kawasaki Medical School, Kurashiki, Japan
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