IN SITU TISSUE REGENERATION. HOST CELL RECRUITMENT AND BIOMATERIAL DESIGN

1. Fundamentals of In Situ Tissue Regeneration
2. Stem Cell Homing
3. Immunology - Host Responses to Biomaterials
4. Foreign Body Reaction and Stem Cell Responses
5. Roles of endogenous growth factors and small peptides in in situ tissue regeneration
6. Small molecules: Controlling cell fate and function
7. Small RNA Delivery for In Situ Tissue Regeneration
8. Micro and Nano Topographical cues guiding biomaterial host response
9. Mechanobiology and Mechanotherapy in Tissue Engineering
10. A biomimetic strategy to design biomaterials for in situ tissue regeneration
11. Impact of Matrix Dynamic Properties on Stem Cell Viability
12. Cell-free Scaffolds for In situ Tissue Regeneration
13. In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design
14. Synovial Joint: In Situ Regeneration of Osteochondral and Fibrocartilaginous Tissues by Homing of Endogenous Cells
15. Bioengineered strategies for tendon regeneration
16. Volumetric Muscle Repair In Situ
17. Mending The Heart Through In Situ Cardiac Regeneration
18. Skin Wound Healing - Skin Regeneration with Pharmacological Mobilized Stem Cells
19. In situ renal regeneration
20. Regulatory Aspects: regulation aspects of cell-free biomaterial implants
21. Business Perspective - case study: commercialized cell-free cardiovascular implant

Features:
• Explores the body’s ability to mobilize endogenous stem cells to the site of injury
• Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity
• Presents smart biomaterials in cell-based tissue engineering applications-from the cell level to applications-in the first unified volume
• Features chapter authors and editors who are authorities in this emerging field
• Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Authors
• Sang Jin Lee, Assistant Professor, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA.
• Anthony Atala, Department of Urology, Wake Forest University, Winston-Salem, NC, USA.
• James J Yoo, Professor, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA