INTRODUCTION TO BILIARY ATRESIA

• Historical Overview of Biliary Atresia
• History and Current Status of The Japanese Biliary Atresia Society
• Definition and Classifications of Biliary Atresia
• Japanese Biliary Atresia Registry
• Embryological and Anatomical Considerations in Biliary Atresia
• Pathogenesis: Overview
• Genetics and Epigenetics in the Pathogenesis of Biliary Atresia
• Pathogenesis: Viral Infection
• Pathogenesis of Maternal Microchimerism
• Epidemiology: Incidence, Gender Ratio, and Ethnic Variations
• Epidemiology: Seasonality, Family History, and Heredity
• Epidemiology of Gestational Age, Birth Weight, and Associated Anomalies in Biliary Atresia
• Screening and Stool Color Card System of Biliary Atresia
• Biliary Atresia: Signs and Symptoms, Prenatal Diagnosis
• Intracranial Hemorrhage in Biliary Atresia
• Pathology of Biliary Atresia
• Biomarkers of Biliary Atresia
• Differential Diagnosis of Biliary Atresia
• Diagnostic Modalities for Biliary Atresia
• Preoperative Management and Direct Cholangiography
• Operative Procedures: Open Kasai Procedure
• Operative Procedures: Laparoscopic Kasai Procedure
• Reoperative Portoenterostomy in Biliary Atresia
• Operation Procedure: Living Donor Liver Transplantation for Biliary Atresia
• Operation Procedure: Deceased Donor Liver Transplantation for Biliary Atresia
• Medical Treatment: Steroids/Ursodeoxycholic Acid
• Medical Treatment: Antioxidant Therapy and Kampo Medicine
• Current Concept About Prevention/Treatment of Postoperative Cholangitis
• Nutritional Support for Patients with Biliary Atresia
• Protocols of Follow-up Management
• Prognostic Indicators of Outcome in Biliary Atresia
• Long-Term Complication after Portoenterostomy: Gastroesophageal and Gastrointestinal Tract Bleeding
• Long-Term Complications: Hypersplenism
• Long-Term Complications: Cholangitis/Gall Stones
• Long-Term Complications: Hepatopulmonary Syndrome
• Long-Term Complications: Portopulmonary Hypertension
• Long-Term Complications of Cirrhosis/Hepatic Encephalopathy
• Long-Term Functional Outcome and Quality of Life After Kasai Operation
• Long-Term Results and Deformities of Intrahepatic Bile Ducts
• Long-Term Results of Liver Transplantation for Biliary Atresia
• Pregnancy and Delivery in Adult Survivors of Biliary Atresia
• Biliary Atresia and Malignancy
• Transition in Biliary Atresia
• Social Support System for Biliary Atresia in Japan
• The Society of the Children with Biliary Atresia and Their Families
• International Collaboration in Biliary Atresia
• Future Prospects of Biliary Atresia
• Clinical Practice Guidelines for Biliary Atresia

This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes.
Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.

Features
• Describes all aspects of biliary atresia.
• Discusses support systems for patients and their families provided by multi-disciplinary medical teams, local communities and the government.
• Highlights the benefits of the laparoscopic Kasai procedure
• Explores the latest early diagnosis and screening methods, such as a stool color card system, which are gradually being introduced throughout the world.