KIDNEY PROTECTION. STRATEGIES FOR RENAL PRESERVATION. A PRACTICAL GUIDE TO PRESERVING RENAL FUNCTION IN ACUTE AND CHRONIC DISEASE

I. Understanding Kidney Disease
1. Epidemiology and Etiology of Kidney disease
2. Pathogenesis of Acute Kidney Injury
3. Adaptations in Acute Kidney Injury: Progression to Chronic Kidney Disease
4. Risk factors for Chronic Kidney Disease
5. Senescence of the Kidney
6. The kidney in Pregnancy
II. Assessment of Kidney Disease
7. Laboratory Investigation of the Kidney
8. Imaging of the Kidney
9. Fundamentals of Kidney Pathology
III. General Concepts in Protecting Kidney Function
10. Pharmacologic renal protection
11. Evaluation and Management of Acute Kidney Injury
12. Slowing progression of Chronic Kidney Disease
13. Renal Artery Stenosis and Revascularization
14. Environmental toxins and the Kidney
15. Peri-operative Renal Protection
16. Renal protection in Critically Ill patients
17. Obstructive Uropathies Priya Deshpande
18. Nephron Sparing Surgery
19. Choice of Renal Replacement Therapy
20. Preserving Residual Renal Function
IV. Drugs and Kidney Function
21. Principles of Drug Therapy in Reduced Kidney Function
22. Acute Kidney Injury from Therapeutic Agents
23. Immunological Agents in the Treatment of Glomerulonephritis Samira Farouk
24. NSAIDs and the Kidney Tonia Kim
25. Contrast and the Kidney
26. Chemotherapeutic agents and the Kidney
27. Poisonings & Intoxications
V. Kidney Protection in systemic illness
28. Diabetes Mellitus and the Kidney
29. Hypertension and the Kidney
30. Cardiovascular Protection in Chronic Kidney Disease
31. Lupus Nephritis
32. Thrombotic Microangiopathies
33. Systemic Inflammatory Diseases and the Kidney
34. The Kidney in patients with Cancer
35. Cast Nephropathy in Plasma cell Dyscrasias
36. Sickle Cell Nephropathy
37. Kidney disease in HIV infection and Treatment
38. Cystic Kidney Diseases
39. Hepatitis Associated Glomerulonephritis
40. Hepatorenal syndrome
41. Cardiorenal syndrome
42. Cardiac surgery and the Kidney
43. Tubulointerstitial Nephropathies
44. Cholesterol Embolism
VI. Kidney Protection in Transplantation
45. High-risk Kidney Transplantation
46. Recurrence of Primary Glomerular Disease Post Kidney Transplantation

Kidney disease affects approximately ten percent of the population worldwide, with more than 2.6 million individuals estimated to be receiving renal replacement therapy. Chronic kidney disease (CKD) is fast becoming a major public health issue, with increasing incidence and death rates throughout the world. Many strategies have been proposed to reduce the growing burden of kidney disease; but while early identification and improved access to renal replacement therapies and transplantation are important, they are unlikely to solve this enormous problem. Efforts focused on primary prevention, protection, and slowing the progression of kidney disease are needed as well. Renal protection is a vital and critical component of protecting the kidneys, promoting recovery, and preventing further renal loss, yet observational data suggests that awareness of renal protection remains low and the concept of renal protection under-recognized..

Kidney Protection: Strategies for Renal Preservation is a clinically focused review that aims to address this awareness and knowledge gap. It assembles clinically pertinent information in a concise and lucid format with the goal of helping the clinician protect the kidneys, whether in the ICU, perioperative, or out-patient setting. The authors' interdisciplinary approach is inclusive of nephrology, urology, critical care, anesthesia, and emergency medicine. Chapters review understanding kidney disease, general concepts in protecting renal function, patient selection, assessment, pharmacologic issues, and kidney protection in systemic illness. The latest evidence-based practical guidelines for optimal renal outcomes are also included.

Features
• First clinical handbook on kidney protection and renal preservation
• Equips clinicians with a practical and reliable resource to help optimize patient outcomes
• Discusses assesment, pharmacologic issues, patient selection, and kidney protection in systemic illness
• Includes current evidence-based clinical guidelines

Authors
• Vijay Lapsia, Assistant Professor of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai.
• Bernard Jaar, Assistant Professor, Department of Epidemiology.
• Ahsan Ejaz, Professor, Division of Nephrology, Hypertension and Renal Transplantation