LIPIDS AND SKIN HEALTH

- Discusses, in depth, our largest organ.
- Addresses the vital role of three types of lipids – epidermal, sebaceous, subcutaneous – on skin health.
- Provides a clear understanding of skin lipids, allowing for better treatment and care of acne, eczema, and the aging skin.

Lipids and Skin Health is the first effort to summarize and review the studies, ideas, and research that link lipid metabolism to the largest organ of our body, the skin. The book covers the fundamental biology of the skin, and the major involvement of the transcriptional factors that govern lipid synthesis and the bioactive lipids in this intriguing organ. All layers of skin are presented, as well as their relevant lipids from the epidermis to dermis and even to the hypodermis. The important and unique-to-skin biological pathways are laid out, with a special focus on the various models that demonstrate the essential role of lipid synthesis in skin pathophysiology. The use of lipids in the cosmetic industry is emphasized, and last but not least the involvement of lipids in the clinical setting is also discussed. This book will appeal to healthcare professionals, researchers and dermatology professionals, and will help them to brainstorm new products and opportunities that will target the emerging importance of lipid metabolism in skin for acne, aging, and healthy skin.

About the Editor
Apostolos Pappas, Ph.D., is a professional member of the Institute of Food Technology. He started his professional career as a research biochemist in the Skin Research Center of Johnson & Johnson and later served as a group leader at Munich Biotech, where he worked on cancer research. Thereafter he returned to Johnson & Johnson, where he is currently a Research Manager and Fellow focusing on lipid metabolism research. He has authored numerous scientific publications, patent applications, and books.

Table of contents (24 chapters)
1.Skin Lipids: An Introduction and Their Importance
2.Skin Basics; Structure and Function
3.Skin Barrier, Structure, and Properties
4.Polyunsaturated Fatty Acid Oxygenated Metabolites in Skin
5.Skin Ceramides
6.Chapter 6 Cholesterol Metabolism in the Epidermis
7.Nuclear Hormone Receptors and Epidermal Differentiation
8.The Brain of the Skin: Sebaceous Gland
9.Sebaceous Lipids
10.Sapienic Acid: Species-Specific Fatty Acid Metabolism of the Human Sebaceous Gland
11.Wax Esters: Chemistry and Biosynthesis
12.Squalene Chemistry and Biology
13.Adipose Tissue and Fat Cell Biology
14.Facial Subcutaneous Adipocytes
15.Stearoyl-CoA Desaturases are Regulators of Lipid Metabolism in Skin
16.Triglyceride Synthesis Enzymes in Skin/Fur
17.Metabolic and Structural Functions of Lipoxygenases in Skin
18.PPAR Gamma Receptor, Skin Lipids and Hair
19.Mineral Oil in Skin Care: Safety Profile
20.Lipophilic Antioxidants
21.Fatty Acids, Fatty Alcohols, Synthetic Esters and Glycerin Applications in the Cosmetic Industry
22.Fats and Oils in Personal Care Products
23.Acne and Lipid Pathways
24.Atopic Dermatitis (AD) and Lipids