MANAGING MYOSITIS. A PRACTICAL GUIDE

Foreword
1 Introduction to Myositis
2 Myositis Basics/Who Gets Myositis
3 Evaluating the patient with suspected myositis
4 Asymptomatic HyperCKemia
5 Clinical Features of Myositis Patients: Muscular Manifestations
6 Clinical Features of Myositis Patients: Skin Manifestations
7 Clinical Features of Myositis Patients: Lung Manifestations
8 Clinical Features of Myositis Patients: Cardiac Manifestations
9 Clinical Features of Myositis Patients: Juvenile Dermatomyositis clinical features
10 Clinical Features of Myositis Patients: Other manifestations: arthritis, Raynaud phenomenon, constitutional
11 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Definition and classification of Myositis
12 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Electrodiagnostic Testing
13 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle biopsy and interpretation
14 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Skin biopsy and interpretation
15 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Lung biopsy and interpretation
16 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Muscle MRI
17 Making the Diagnosis of Myositis: Beyond the History and Physical Examination: Laboratory testing in myositis
18 Role of ANA and Myositis Autoantibodies in Diagnosis
19 Role of Myositis Autoantibodies in Management and Prognosis
20 Traditional Myositis Autoantibodies: Synthetase, Mi-2, SRP, Ku, PM-Scl, Ro, U1RNP
21 Dermatomyositis-associated Autoantibodies: TIF1- , NXP2, and MDA5
22 Newly described Myositis Autoantibodies: HMGCR, NT5C1A, SAE, PUF60
23 Myositis Mimics: The Differential Diagnosis of Myositis
24 Immune Mediated Necrotizing Myopathy (IMNM)
25 Cancer Associated Myositis
26 Myositis Associated Interstitial Lung Disease
27 Pregnancy in Myositis
28 Pathogenesis of Myositis
29 Management Considerations: Pharmacologic intervention
30 Management Considerations:Special treatment considerations - JDM
31 Management Considerations: Special treatment considerations - Refractory skin rash and calcinosis
32 Management Considerations: Special treatment considerations - ILD
33 Role of Exercise in the Management of Myositis
34 Dietary Considerations in Myositis
35 Distinguishing Disease Activity and Damage in Myositis

This comprehensive book serves as a guide in the day-to-day management of patients with idiopathic inflammatory myopathies (IIM), with a particular emphasis on adult dermatomyositis (DM), polymyositis (PM), juvenile dermatomyositis, necrotizing myositis, and inclusion body myositis. Practical in nature, it presents IIM concepts in a straightforward fashion, with high-quality figures, algorithms, and flowcharts supplementing each of the expertly authored chapters. The book begins with an introduction to myositis, providing an overview of the myositis basics and what type of patient is affected. Subsequent chapters are organized by the sequence in which a physician often manages myositis, from initial presentation and workup, to diagnosis, treatment, and finally prognostic and long-term outcome factors. The key differentials in various diagnostic studies are thoroughly examined, including electromyography, muscle biopsy, and MRI. Managing Myositis: A Practical Guide is an easy to-read, indispensable resource for internists, rheumatologists, dermatologists, pulmonologists, and neurologists.

Features
• Offers practical guidelines for the diagnosis and treatment of patients with inflammatory myopathies
• Covers a variety of disorders such as polymyositis, dermatomyositis, and immune mediated necrotizing myopathy
• Discusses history, physical examination, differential diagnosis, use of diagnostic tests, and management
• Presents practical guidance on the assessment and longitudinal management of myositis and associated co-morbidities

Authors
• Rohit Aggarwal, MD, MS. Associate Professor of Medicine. University of Pittsburgh
School of Medicine. Medical Director, Arthritis and Autoimmunity Center. Co-Director of the UPMC Myositis Center. Pittsburgh, PA 15260 USA
• Chester V. Oddis, MD. Professor of Medicine . University of Pittsburgh . School Of Medicine
Director of the Myositis Center. Pittsburgh, PA 15260. USA