MANUAL OF BOTULINUM TOXIN THERAPY. 3RD EDITION

1. The pretherapeutic history of botulinum neurotoxin;
2. Botulinum neurotoxin: History of Clinical development;
3. Pharmacology of botulinum toxin therapy;
4. Immunological properties of botulinum neurotoxins;
5. Examination and treatment of complex cervical dystonia;
6. Visualization of ultrasound guided intramuscular injections in muscles relevant for cervical dystonia;
7. Ultrasound guidance for botulinum neurotoxin therapy: cervical dystonia;
8. Treatment of cervical dystonia;
9. Treatment of blepharospasm;
10. Botulinum neurotoxin in oromandibular dystonia;
11. Botulinum neurotoxin therapy of laryngeal muscle hyperactivity syndromes;
12.The use of botulinum neurotoxin in otorhinolaryngology;
13. Treatment of Hemifacial Spasm with Botulinum Toxin;
14. Botulinum toxin in treatment of tics;
15. The use of botulinum toxin in tremors;
16. The role of ultrasound for botulinum neurotoxin injection in childhood spasticity;
17. The use of botulinum neurotoxin in spastic infantile cerebral palsy;
18. The use of botulinum neurotoxin in spasticity using ultrasound guidance;
19. The use of botulinum toxin in spasticity;
20. Treatment of stiff-person syndrome with botulinum toxin;
21. Botulinum toxin in ophthalmology;
22. Cosmetic uses of botulinum neurotoxins for the upper face;
23. Botulinum toxin on the lower face;
24. Botulinum Toxin in the treatment of Gummy Smile;
25. Botulinum toxin for the breast;
26. Treatment of depression with botulinum toxin;
27. Hyperhidrosis Berthold: A treatment for ischemic digits and chronic pain;
28. Botulinum toxin in the treatment for ischemic digits and chronic pain;
29. Botulinum Toxin in Wound Healing;
30. Use of botulinum neurotoxin in neuropathic pain;
31. The Use of botulinum toxin in the management of headache disorders;
32. Use of Botulinum Toxin in Musculoskeletal Pain and Arthritis;
33. Treatment of plantar fasciitis/plantar fasciopathy with botulinum neurotoxins;
34. Use of botulinum toxin in the treatment of low back pain;
35. Use of botulinum neurotoxin in the treatment of piriformis syndrome;
36. Ultrasound guided botulinum toxin injections for thoracic outlet syndrome;
37. Botulinum neurotoxin in the gastrointestinal tract;
38. Botulinum neurotoxin applications in urological disorders;
39. Treatment of focal hand dystonia.

Providing practical, visually oriented guidance on the benefits of botulinum toxin in a wide variety of disorders, some new and
unexpected, this new edition of Manual of Botulinum Toxin Therapy is fully updated in scope and detail. Chapters discuss the
pathophysiology of each condition, summarizing the rationale for botulinum toxin, and describing the injection approach. Clear
illustrations of the injection sites are included, using a ‘clinician’s eye’ perspective, which allows physicians to readily identify
anatomical landmarks and approach angles for injection. Dosing tables for available toxin formulations are included. The Manual
covers cosmetic treatment of the upper and lower face, as well as aesthetic smile correction. Extensive guidance on how to use
ultrasound and how cadaveric dissections can assist localization and targeting of injections is provided. Designed for teaching and
bedside guidance, the Manual is useful to a diverse range of clinicians looking to use botulinum toxin in their practice.

Key Features
• Chapters are authored by internationally renowned clinicians and investigators, ensuring content is cutting edge and valuable to
professionals worldwide
• Clear and eye-catching illustrations show a ‘clinician’s eye view’ of the injection procedure, allowing practitioners to readily
identify anatomical landmarks and approach angles for injection
• Providing extensive instruction in the use of ultrasound, correlating probe positioning, on-screen image and illustrations or
dissection photos of injection targets, readers will learn about the fastest growing modality for injection guidance