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Contributors iii
Foreword ix
Preface for the Fifth Edition x
Acknowledgments xi
• SECTION I: Basics of Healthcare Epidemiology and Infection Prevention
CHAPTER 1 Principles of Healthcare Epidemiology 1
CHAPTER 2 Infectious Disease Surveillance in Healthcare Settings 21
CHAPTER 3 Isolation of Patients With Communicable Diseases 30
CHAPTER 4 Hand Hygiene 53
CHAPTER 5 Role of the Microbiology Laboratory and Molecular Diagnostics in Healthcare Epidemiology and Infection Prevention 69
CHAPTER 6 Legal Issues in Healthcare Epidemiology and Infection Prevention 81
CHAPTER 7 Ethical Issues in Healthcare Epidemiology and Infection Prevention 91
• SECTION II: Tools/Skills for the Modern Healthcare Epidemiologist
CHAPTER 8 Quality Improvement for Healthcare Epidemiology: Creating a Culture of Excellence 97
CHAPTER 9 Investigation of Outbreaks 105
CHAPTER 10 Developing an Infection Prevention Program 119
CHAPTER 11 Communication and Messaging Strategies in Infection Prevention 127
• SECTION III: Epidemiology and Prevention of Healthcare-Associated Infections
CHAPTER 12 Healthcare-Associated Infections Related to the Use of Intravascular Devices 139
CHAPTER 13 Healthcare-Associated Bloodstream Infections 153
CHAPTER 14 Healthcare-Associated Urinary Tract Infections (Including CAUTI) 169
CHAPTER 15 Surgical Site Infections 183
CHAPTER 16 Hospital-Acquired Pneumonia and Ventilator-Associated Events 198
CHAPTER 17 Clostridioides (Clostridium) difficile 216
CHAPTER 18 Healthcare-Associated Gastrointestinal Illness 227
CHAPTER 19 MDRO Infections: Gram-Positive Organisms (Including Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus) 243
CHAPTER 20 MDRO Infections: Gram-Negative Organisms 286
CHAPTER 21 Healthcare-Associated Fungal Infections (Candida and Invasive Molds) 306
CHAPTER 22 Healthcare-Associated Viral Respiratory Infections 318
CHAPTER 23 Mycobacterium tuberculosis 325
CHAPTER 24 Nontuberculous Mycobacteria 347
CHAPTER 25 Epidemiology and Prevention of Healthcare-Associated Infections Related to Animals in the Hospital 358
• SECTION IV: Epidemiology and Prevention of Healthcare-Associated Infections in Special Patient Populations and Healthcare Settings
CHAPTER 26 Healthcare-Associated Infections in Obstetric Patients 368
CHAPTER 27 Healthcare-Associated Infections in Burn Patients 378
CHAPTER 28 Healthcare-Associated Eye Infections 401
CHAPTER 29 Infection Prevention Issues Unique to Newborns and the Neonatal Intensive Care Unit 410
CHAPTER 30 Infection Prevention and Control in Hematopoietic Stem Cell Transplant and Oncology Patients 427
CHAPTER 31 Healthcare-Associated Infections in Solid Organ Transplant Recipients 440
CHAPTER 32 Epidemiology and Prevention of Infections in Long-term Care Facilities 455
CHAPTER 33 Infection Prevention and Control in Resource-Limited Settings 470
• SECTION V: Infections Related to Diagnostic and Therapeutic Procedures
CHAPTER 34 Healthcare-Associated Infections in Anesthesia 480
CHAPTER 35 Dialysis-Associated Infections 490
• SECTION VI: Epidemiology and Prevention of Healthcare-Associated Infections in Healthcare Workers
CHAPTER 36 Developing an Occupational Infection Prevention Program 516
CHAPTER 37 Vaccination of Healthcare Personnel 524
CHAPTER 38 Exposures to Blood-Borne Pathogens 546
CHAPTER 39 Exposures to Contagious Infectious Diseases 581
• SECTION VII: Prevention of Healthcare-Associated Infections Related to the Hospital Environment, Sterilization, and Disinfection
CHAPTER 40 High-Level Disinfection and Sterilization 589
CHAPTER 41 Prevention of Infections Related to Construction, Renovation, and Demolition in Healthcare Facilities 611
CHAPTER 42 Infection Prevention and the Physical Environment 626
CHAPTER 43 Prevention of Waterborne Infections (Including Legionella) 638
• SECTION VIII: Reducing Antimicrobial Resistance in Healthcare Settings Through Antimicrobial Stewardship
CHAPTER 44 Developing an Antimicrobial Stewardship Program in the Hospital Setting 647
CHAPTER 45 Interventions to Optimize Antimicrobial Use 660
CHAPTER 46 Antibiotic Stewardship in Long-term Care Settings 671
CHAPTER 47 Antimicrobial Stewardship in Outpatients 685
• SECTION IX: Emergency Preparedness
CHAPTER 48 Developing an Emergency Preparedness Program 693
CHAPTER 49 Emergency Preparedness: Highly Communicable Respiratory Infections 704
CHAPTER 50 Emergency Preparedness: Highly Communicable Infections Transmitted by Contact 712
Index 727

The fifth edition of Mayhall’s Hospital Epidemiology and Infection Prevention has a new streamlined focus, with new editors and contributors, a new two-color format, and a new title. Continuing the legacy of excellence established by Dr. C. Glen Mayhall, this thoroughly revised text covers all aspects of healthcare-associated infections and their prevention and remains the most comprehensive reference available in this complex field. It examines every type of healthcare-associated (nosocomial) infection and addresses every issue relating to surveillance, prevention, and control of these infections in patients and in healthcare personnel, providing unparalleled coverage for hospital epidemiologists and infectious disease specialists.

• Covers the basics of hospital epidemiology and infection prevention, types of healthcare-associated infections, details of specific pathogens (bacterial, mycobacterial, fungal, and viral), special populations, prevention of infections related to specific procedures as well as the hospital environment, antibiotic stewardship, occupational health, and emergency preparedness, among other key topics.
• Focuses on the evidence, science, and operational insight critical to the detection, transmission, and prevention of healthcare-associated infections (HAIs).
• Includes chapters centered on specific types of HAIs (CLABSI, CAUTI, SSI, for example) and specific healthcare settings and patient populations (such as burn units, neonatal ICUs, and transplant recipients).
• Includes two several entirely new chapters on antimicrobial stewardship.
• Reflects new, user-friendly features such as the placement of core basic skills like HAI surveillance, isolation practices, and outbreak investigation earlier in the book; bulleted key points at the beginning of each chapter; full reference lists in every chapter; more figures and illustrations; and updated charts and graphs throughout.

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