Descuento:
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Despues:
140,60 €1. Using the Flp recombinase to induce site-specific nicks
2. Synthesis from D-loops
3. Bacteriophage T4 system as a model for recombination/replication interface
4. Inducing and detecting mitotic DNA synthesis at difficult-to-replicate loci
5. Reporter system to study the RNA-DNA recombination
6. Assaying recombination and mutagenesis at DNA nicks
7. Recovery of alternative end-joining repair products from Drosophila embryos
8. High-throughput analysis of DNA break-induced chromosome rearrangements by amplicon sequencing
9. Analysis of mutagenesis associated with recombination
10. Investigation of break-induced replication in yeast
11. Dissecting the dual endo- and exonuclease activity of MRE11 (MRN) with small molecules
12. RAD52 inhibition
13. Structure-guided, fragment-based drug discovery against RAD51 recombinase: targeting a protein-peptide interface
14. Molecular intermediates of recombination in meiosis (methods, like 2D, and others)
15. S1-seq method for mapping DSB resection endpoints
16. Methods for studying the roles of the Sgs1-Top3-Rmi1 helicase/decatenase complex in meiotic recombination intermediate metabolism
17. Live cell imaging of heterochromatin repair in Drosophila cells
18. Analysis of meiotic double-strand break initiation in mammals
• Contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability
• Documents cutting edge methods
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