Part 1: How does the microbiome influence human health
1.The “normal” gut microbiome and human health
2. The “normal” oral microbiome and human health
3. The “normal” eye microbiome and human health
4. What is microbial dysbiosis and how does it impact human health
5. Immune responses to microbial dysbiosis
6. Microbiome and wound healing
Part 2: Microbiome alterations and eye disease
7. Microbiome alterations and ocular surface diseases (dry eye and allergy)
8. Microbiome alterations and keratitis
9. Microbiome abnormalities and uveitis
10. Microbiome abnormalities and glaucoma
11. Microbiome abnormalities and retinal disease
12. Microbiome manipulation as a target for eye diseases: Lessons from animal models
13. Microbiome manipulation as a target for eye diseases: Lessons from humans
Microbiome and the Eye: What’s the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians.
The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.
• Helps researchers understand the clinical eye diseases that have been linked to gut microbiome abnormalities
• Helps clinicians understand the mechanisms in which gut microbiome composition may influence health in multiple compartments
• Provides a foundation for future studies that consider gut microbiome manipulations as a treatment for specific eye diseases
• Anat Galor, Staff Physician, Miami Veterans Affairs Medical Center, Associate Professor of Clinical Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
• Jun Sun, Professor of Gastroenterology and Hepatology, University of Illinois at Chicago College of Medicine, Chicago, Illinois, USA