NEUROENDOCRINE TUMOURS. DIAGNOSIS AND MANAGEMENT

Since neuroendocrine tumors (NETs) are relatively rare, they have in the past attracted limited research interest and only a small number of oncologists have regarded them as a special concern. Fortunately, this situation is changing. There have been significant recent developments in our understanding of NETs and new treatment options have become available, stimulating a focus on further research and the scope for additional therapeutic advances. Neuroendocrine Tumors is therefore a timely textbook that covers all aspects of the subject, from epidemiology, pathological classification and evaluation, and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas, and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists, and pathologists and also trainees.

Table of contents (33 chapters)
1.Introduction to Neuroendocrine Tumours
2.History of Neuroendocrine Tumors
3.Epidemiology of Neuroendocrine Tumors
4.Molecular Biology of Neuroendocrine Tumors
5.Genetic Syndromes Associated with Neuroendocrine Tumours
6.Pathological Evaluation and Classification of Digestive Neuroendocrine Tumours
7.Circulating Biomarkers in Neuroendocrine Tumours
8.Cross-Sectional Imaging of Neuroendocrine Tumours
9.Nuclear Medicine Imaging in Neuroendocrine Tumors
10.Neuroendocrine Tumors of the Lung
11.Overview of Gastrointestinal Neuroendocrine Tumours
12.Insulinoma
13.Gastrinoma
14.VIPoma and PPoma
15.Glucagonoma
16.Somatostatinoma
17.Less Common Types of Pancreatic Neuroendocrine Tumors
18.Nonfunctioning Pancreatic Neuroendocrine Tumors
19.Gastroenteropancreatic Neuroendocrine Carcinoma
20.The Multiple Endocrine Neoplasia Syndromes
21.Thyroid Cancer
22.Medullary Thyroid Cancer
23.Diagnosis and Management of Adrenocortical Carcinomas
24.Pheochromocytoma and Paraganglioma
25.Surgical Approach in the Treatment of Neuroendocrine Tumours
26.Liver-Directed Therapies in Neuroendocrine Tumors
27.Peptide Receptor Radionuclide Therapy
28.Management of Hormonal Symptoms
29.Carcinoid Syndrome
30.Somatostatin Analogs and Interferon in the Treatment of Neuroendocrine Tumors
31.Chemotherapy
32.Targeted Therapies
33.Societies and Guidelines for Neuroendocrine Tumors