POLYCYSTIC KIDNEY DISEASE. TRANSLATING MECHANISMS INTO THERAPY

POLYCYSTIC KIDNEY DISEASE. TRANSLATING MECHANISMS INTO THERAPY

Editorial:
SPRINGER
Año de edición:
Materia
Nefrología
ISBN:
978-1-4939-7782-6
Páginas:
271
N. de edición:
1
Idioma:
Inglés
Ilustraciones:
62
Disponibilidad:
Disponible en 2-3 semanas

Descuento:

-5%

Antes:

93,60 €

Despues:

88,92 €

1. Classical Polycystic Kidney Disease: Gene Structures and Mutations and Protein Structures and Functions
2. Bardet-Biedl Syndrome
3. Cystic Kidney Diseases Associated with Increased Cancer Risk: Tuberous Sclerosis Complex, Von Hippel-Lindau, and Birt-Hogg-Dubé
4. Aberrant Cellular Pathways in PKD
5. Cilia and Polycystic Kidney Disease
6. The Role of Inflammation and Fibrosis in Cystic Kidney Disease
7. Imaging-Based Diagnosis of Autosomal Dominant Polycystic Kidney Disease
8. Renal Structural Involvement in Autosomal Dominant Polycystic Kidney Disease: Cyst Growth and Total Kidney Volume – Lessons from the Consortium for Radiologic Imaging of Polycystic Kidney Disease (CRISP)
9. Renal Complications: Pain, Infection, and Nephrolithiasis
10. Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease: Polycystic Liver Disease
11. Other Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease
12. Role of Renin-Angiotensin-Aldosterone System Inhibition in Autosomal Dominant Polycystic Kidney Disease
13. Vasopressin Receptor Antagonism in PKD
14. End-Stage Renal Disease in Patients with Autosomal Dominant Polycystic Kidney Disease
15. Management of ADPKD Today

This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD’s clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource.

Features
• Provides a comprehensive review of PKD mutations, pathophysiologic mechanisms of PKD, renal and extrarenal manifestations of PKD, clinical trials and emerging therapies in PKD, and appropriate management of patients with PKDWritten by top professionals in the field
• Well-illustrated resource serves both clinician and researcher

Authors
• John J. Bissler, MD. Federal Express Chair of Excellence, Professor and Chief, Division of Nephrology, Department of Pediatrics, Director of the Tuberous Sclerosis Center of Excellence at Le Bonheur Children’s Hospital, Medical Director of Nephrology, St. Jude Children's Research Hospital, University of Tennessee Health Science Center University of Tennessee Health Science Center. Children’s Foundation Research Center. Memphis, TN
• Benjamin D. Cowley, Jr., M.D., F.A.C.P., F.A.S.N. Professor of Medicine. Chief, Nephrology & Hypertension. John Gammill Professor in Polycystic Kidney Disease. University of Oklahoma Health Sciences Center. Oklahoma City, OK