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Contributing Authors v
Preface xiii
Acknowledgments xv
• SECTION 1 Symptoms and Syndromes 1
Part A: Pain
1. Neuropathic, Bone, and Visceral Pain Syndromes 2
2. Opioid Pharmacotherapy 22
3. Nonpharmacologic Management of Pain 44
4. Interventional Approach to Pain 58
5. Treatment Planning in Palliative Radiotherapy 70
6. Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy 88
Part B: Constitutional Symptoms
7. Cancer-Related Fatigue 100
8. Fever and Sweats 114
9. Hot Flashes 127
Part C: Gastrointestinal Symptoms and Syndromes
10. Anorexia/Weight Loss 141
11. Swallowing and Speech Considerations in Palliative Care 164
12. Chemotherapy-Related Nausea and Vomiting and Treatment-Related Nausea and Vomiting 180
13. Assessment and Management of Chronic Nausea and Vomiting 194
14. Diarrhea, Malabsorption, and Constipation 207
15. Bowel Obstruction 226
16. Diagnosis and Management of Effusions 245
17. Hiccups and Other Gastrointestinal Symptoms 258
18. Oral Manifestations and Complications of Cancer Therapy 273
Part D: Skin
19. Pruritus 295
20. Management of Tumor-Related Skin Disorders 307
21. Dermatologic Adverse Events during Treatment 322
22. Management of Pressure Injury, Fungating Malignant Wounds, Fistulas, and Stomas 337
23. Lymphedema 352
Part E: Cardiopulmonary and Vascular Syndromes
24. Dyspnea in the Cancer Patient 366
25. Hemoptysis, Airway Obstruction, Bronchospasm, Cough, and Pulmonary Complications/Symptoms of Cancer and Its Treatment 380
26. Prevention, Assessment, and Management of Treatment-Induced Cardiac Disease in Cancer Patients 396
27. Noninvasive Respiratory Support and Palliative Care 410
Part F: Genitourinary Symptoms and Syndromes
28. Urologic Issues in Palliative Care 421
Hiren V . Patel, Brian Shinder, Adam R.
Metwalli, Peter A. Pinto, and Eric A. Singer
29. Impact of Hepatic and Renal Dysfunction on
Pharmacology of Palliative Care Drugs 443
Katelyn Stepanyan and Thomas Strouse
Part G: Metabolic Disorders
30. Metabolic Disorders in the Cancer Patient 451
31. Infectious Complications/Management 465
Part H: Selected Neurologic Symptoms and Syndromes
32. Management of Intracranial Metastases 482
33. Management of Spinal Cord and Cauda Equina Compression 494
Part I: Selected Psychiatric Symptoms and Syndromes
34. Recognizing and Managing Delirium 512
35. Depression and Anxiety in Palliative Care 526
36. Cognitive Decline Following Cancer Treatment 554
37. Substance Use Disorders and Palliative Care 570
• SECTION II Issues in Palliative Care 584
Part A: Definitions and Models
38. Hospice 585
Part B: Assessment Issues
39. Cultural Issues in Palliatives and Supportive Oncology 595
40. Communication During Transitions of Care 600
41. The Family Meeting 614
Part C: Other Issues in Palliative Care
42. Psychosocial Consequences of Advanced Cancer 626
43. Disorders of Sexuality and Reproduction 645
44. Caregiving in the Home 656
45. Management of Symptoms in the Actively Dying Patient 670
46. Spirituality 683
47. Grief and Bereavement 703
48. Staff Stress and Burnout 713
• SECTION III Ethical Considerations in Palliative Care 725
49. Advance Care Planning, Advance Directives, and Withholding and Withdrawing Treatment 726
50. Palliative Care: Ethics and the Law 736
51. Assisted Suicide or Understanding and Responding to Requests for Hastened Death 750
• SECTION IV Special Interventions in Supportive and Palliative Care 765
52. Hematologic Support of the Cancer Patient 766
53. Issues in Nutrition and Hydration 785
54. Complementary and Integrative Therapies in Oncology 797
55. Cannabinoids 821
• SECTION V Special Populations 829
56. Geriatric Palliative Care 830
57. Palliative Care in Pediatrics 840
58. Hematopoietic Cell Transplantation and Supportive Care 879
59. Survivorship Issues in Pediatrics 894
60. Survivorship Issues in Adults 911
61. Cancer Genetics and Palliative Care 938
62. Palliative and Supportive Care: The Global Context 962
• SECTION VI Research Issues in Supportive Palliative Care 971
63. Outcomes Assessment in Palliative Care 972
64. Research Issues: Ethics and Study Design 981

Index 991

TThe only book on the market to cover palliative care for both adults and children, Pediatric and Adult Palliative Care and Support Oncology offers an easy-to-read, interdisciplinary approach to supportive oncology as well as end-of-life care. Ideal for oncologists, residents, fellows, nurse practitioners, and physician assistants, the fifth edition provides important updates for conventional topics while also featuring several brand new chapters. Covering everything from dermatologic toxicity of cancer treatment to running family meetings for setting goals of care, this unique title is a source of both help and inspiration to all those who care for patients with cancer.

• Offers an interdisciplinary approach to supportive oncology, providing practical ways to implement integrated care to patients and families who live with cancer.
• Covers common issues such as pain, fatigue, nausea, and vomiting—both the physical symptoms and the psychosocial/spiritual effects—helping the reader understand practical ways of integrating curing and healing.
• Features entirely new chapters covering emerging topics in the field of palliative care, such as cannabinoids, survivorship issues in pediatrics, and cancer genetics.
• Provides expert guidance from contributing authors in medial, radiation, and surgical oncology, as well as nursing, neurology, psychiatry, anesthesiology, and pharmacology.

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