PRINCIPLES OF NEONATOLOGY

• Section 1: Care of the Premature and Critically-Ill Neonate
1 Design of Neonatal Intensive Care Units, 2
2 NICU Environment for Parents and Staff, 7
3 Safe Use of Health Information Technology, 12
4 Pharmacologic Management of Neonatal Pain and Agitation, 18
5 Neonatal Transport, 27
6 Radiation Safety in Premature and Critically-Ill Neonates, 33
• Section 2: Neonatal Resuscitation and Respiratory Care
7 Placental Transfusion in the Newborn, 38
8 Neonatal Resuscitation, 44
9 Golden Hour and Thermoregulation, 57
10 Oxygen During Postnatal Stabilization, 62
11 Respiratory Distress Syndrome, 66
12 Invasive and Noninvasive Ventilation Strategies, 78
13 Pulmonary Hypertension of the Newborn, 88
14 Bronchopulmonary Dysplasia, 98
15 Treatment of Apnea of Prematurity, 106
• Section 3: Feeding
16 Human Milk, 112
17 Storage and Use of Human Milk in Neonatal Intensive Care Units, 120
18 Possible Benefits and Risks of Using Probiotics in Neonates, 128
• Section 4: Nutrition
19 Enteral Nutrition, 142
20 Parenteral Nutrition in Neonates, 156
21 Nutrition in Short Bowel Syndrome, 170
22 Neonatal Nutrition Assessment, 178
• Section 5: Endocrine Disorders
23 Neonatal Hypoglycemia, 193
24 Infants of Diabetic Mothers, 200
25 Evidence-Based Neonatology: Neonatal Pituitary Hormone Deficiencies, 207
26 Neonatal Thyroid Disease, 215
27 Hypothalamic-Pituitary-Adrenal Axis in Neonates, 222
28 Disorders of Neonatal Mineral Metabolism and Metabolic Bone Disease, 230
29 Disorders of Sex Development for Neonatologists, 241
• Section 6: Infections
30 Early-Onset Sepsis, 251
31 Late-Onset Sepsis, 257
32 Neonatal Herpes Simplex Virus Infections, 261
33 Postnatal Cytomegalovirus Infection Among Preterm Infants, 268
34 Congenital Syphilis, 274
35 Invasive Fungal Infections in the NICU: Candida, Aspergillosis, and Mucormycosis, 279
• Section 7: Cardiac Defects and Dysfunction
36 Congenital Heart Defects, 291
37 Cardiac Defects—Anatomy and Physiology, 299
38 Medical and Surgical Management of Critical Congenital Heart Disease, 317
39 Neonatal Arrhythmia and Conduction Abnormalities, 326
40 Pulmonary Hypertension in Chronic Lung Disease, 336
41 Hemodynamic Assessment and Management of a Critically Ill Infant, 344
• Section 8: Jaundice, Blood Disorders, and Transfusions
42 A Practical Guide to Evaluating and Treating Severe Neonatal Indirect Hyperbilirubinemia, 351
43 Neonatal Anemia, 357
44 Evidence-Based Neonatal Transfusion Guidelines, 380
45 Neonatal Thrombocytopenia, 387
• Section 9: Neurological Disorders
46 Management of Hypoxic-Ischemic Encephalopathy Using Therapeutic Hypothermia, 400
47 Management of Hypoxic-Ischemic Encephalopathy Using Measures Other Than Therapeutic Hypothermia, 406
48 Management of Encephalopathy of Prematurity, 421
49 Neonatal Seizures, 427
50 Stroke in Neonates, 438
51 Using Biomarkers for Management of Perinatal Brain Injury, 444
52 Intraventricular Hemorrhage and Posthemorrhage Hydrocephalus, 447
53 Management of Neurotrauma, 456
54 Management of Myelomeningocele and Related Disorders of the Newborn, 462
55 Treating Neonatal Abstinence Syndrome in the Newborn, 470
• Section 10: Immunology
56 Neonatal Immunity, 484
57 Immunodeficiency Syndromes Seen During the Neonatal Period, 498
• Section 11: Kidney
58 Neonatal Acute Kidney Injury, 508
59 Renal Replacement Therapy, 519
60 Neonatal Hypertension, 525
61 Altered Development of the Kidneys and the Urinary Tract, 533
• Section 12: Eye Disorders
62 Retinopathy of Prematurity, 545
63 Developmental Anomalies of the Globe and Ocular Adnexa in Neonates, 552
64 Developmental Anomalies of the Cornea and Iris in Neonates, 560
65 Cataract and Glaucoma, 570
• Section 13: ENT and Auditory Conditions
66 Neonatal Tracheostomy, 577
67 Stridor and Laryngotracheal Airway Obstruction in Newborns, 582
68 Pierre-Robin Sequence/Cleft Palate-Related Airway Obstruction Seen in Neonates, 592
69 Congenital Hearing Loss Seen in Neonates, 597
70 Nasal Obstruction in Newborn Infants, 607
• Section 14: Orthopedic Conditions
71 Upper Extremity Conditions in the Neonate, 618
72 Newborn Spine Deformities, 624
73 Hip and Lower Extremity Deformities, 631
74 Fractures and Musculoskeletal Infections in the Neonate, 641
• Section 15: Inborn Errors of Metabolism and Newborn Screening
75 Most Frequently Encountered Inborn Errors of Metabolism, 649
76 Screening Programs for Early Detection of Inborn Errors of Metabolism in Neonates, 661
• Section 16: Genetic Conditions (Including Microarrays, Exome Sequencing)
77 An Overview of Genetic Testing, 671
78 Genetics of Common Birth Defects in Newborns, 677
79 Common Monogenetic Conditions in Newborns, 690
80 Common Chromosomal Conditions in Newborns, 699
• Section 17: Neonatal Surgical Conditions
81 Necrotizing Enterocolitis, 707
82 Extracorporeal Membrane Oxygenation in Neonates, 715
83 Intestinal Surgery in the Newborn—Atresias, Volvulus, and Everything Else, 720
84 Pulmonary Surgery in the Newborn, 727
85 Congenital Anorectal Malformations and Hirschsprung Disease in the Neonate, 738
86 Esophageal Surgery in Neonates: Esophageal Atresia, Gastroesophageal Reflux, and Other Congenital Anomalies, 745
• Section 18: Current State of Neonatal Palliative Care
87 Caring for Families Who Have Previously Endured Multiple Perinatal Losses, 754
88 Current State of Perinatal Palliative Care: Clinical Practice, Training, and Research, 758
89 Serious Communication in the Neonatal Intensive Care Unit: Evidence for Strategies and Training, 765
90 Pain and Symptom Management in Newborns Receiving Palliative and End-of-Life Care, 776
91 Palliative Care Family Support in Neonatology, 783
• Section 19: Follow-Up
92 Early Diagnosis and Intervention in Neonatal Intensive Care Units, 791
93 Early Diagnosis and Intervention—On Neonatal Follow-Up, 797
94 Early Detection of Cerebral Palsy, 802
95 Use of Neuroimaging to Predict Adverse Developmental Outcomes in High-Risk Infants, 812
96 Neurodevelopmental Impairment in Specific Neonatal Disorders, 823
• Section 20: Designing Clinical Trials in Neonatology
97 Quality Improvement in Neonatal Care, 833
98 Neonatal Randomized Controlled Trials, 838
99 Designing Clinical Trials in Neonatology—International Trials, 845
• Section 21: Healthcare Leadership
100 Organization of Neonatal Intensive Care, 851
101 Leadership and Organizational Culture in Healthcare, 856
• Section 22: Neonatal Dermatology
102 Skin Disorders in Newborn Infants, 862

Written by leading global experts in the field, Principles of Neonatology provides those on the NICU team with clinically focused, evidence-based guidance in an easy-to-access format. Chapters cover the key topics of greatest and most frequent concern to clinicians treating newborns, delivering current, data-driven management and treatment advice in a single source relevant to the seasoned practitioner, fellow, or trainee.

Features:
• A highly templated format makes it easy to find exactly the information you need.
• Lavishly illustrated with photos, radiographs, drawings, and charts and graphs that clarify key concepts in a helpful and accessible way.
• Evidence-based focus ensures that only the most reliable treatment protocols and clear-cut, data-driven guidance are included.
• Coverage of all relevant topics in the NICU: skin lesions, congenital anomalies, architecture/development of neonatal intensive care units, pain control, anesthesia for newborn infants, and much more.
• Ideal for every member of the NICU team: neonatologists, neonatology fellows, residents, and neonatal nurses, as well as all other clinicians working in the NICU, including PAs, occupational therapists, respiratory therapists, and others.
• An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.