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Now in its 10th edition, Sleisenger and Fordtran’s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments-with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos.

- Get the essential gastroenterology information you need from one authoritative source with an outstanding global reputation for excellence.
- Zero in on the key information you need to know with a consistent, full-color chapter design.

New To This Edition:
- Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases.
- Incorporate the latest findings and improvements in care for liver disease patients-from diagnosis and treatment through post-treatment strategies and management of complications.
- Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Mark Feldman, MD, William O. Tschumy Jr., MD, Chair of Internal Medicine, Director, Internal Medicine Residency Program, Texas Health Presbyterian Hospital Dallas; Clinical Professor of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas.

Lawrence S. Friedman, MD, Professor of Medicine, Harvard Medical School; Professor of Medicine, Tufts University School of Medicine, Boston, Massachusetts; The Anton R. Fried, MD, Chair, Department of Medicine, Newton-Wellesley Hospital, Newton, Massachusetts; Assistant Chief of Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Lawrence J. Brandt, MD, Professor of Medicine and Surgery, Albert Einstein College of Medicine, Emeritus Chief, Division of Gastroenterology, Montefiore Medical Center, Bronx, New York.

Section I. Biology of the Gastrointestinal Tract
1. Cellular Growth and Neoplasia
2. Mucosal Immunology and Inflammation
3. Enteric Microbiota
4. Gastrointestinal Hormones and Neurotransmitters

Section II. Nutrition in Gastroenterology5. Nutritional Principles and Assessment of the Gastroenterology Patient
6. Nutritional Management
7. Obesity
8. Surgical and Endoscopic Treatment of Obesity
9. Feeding and Eating Disorders
10. Food Allergies

Section III. Symptoms, Signs, and Biopsychosocial Issues11. Acute Abdominal Pain
12. Chronic Abdominal Pain
13. Symptoms of Esophageal Disease
14. Dyspepsia
15. Nausea and Vomiting
16. Diarrhea
17. Intestinal Gas
18. Fecal Incontinence
19. Constipation
20. Gastrointestinal Bleeding
21. Jaundice
22. Biopsychosocial Issues in Gastroenterology
23. Factitious Gastrointestinal Disease

Section IV. Topics Involving Multiple Organs
24. Oral Disease and Oral-Cutaneous Manifestations of Gastrointestinal and Liver Disease
25. Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine
26. Abdominal Hernias and Gastric Volvulus
27. Foreign Bodies, Bezoars, and Caustic Injury
28. Abdominal Abscesses and Gastrointestinal Fistulas
29. Eosinophilic Disorders of the Gastrointestinal Tract
30. Protein-Losing Gastroenteropathy
31. Gastrointestinal Lymphomas
32. Gastrointestinal Stromal Tumors (GISTs)
33. Neuroendocrine Tumors
34. Gastrointestinal Consequences of Infection With Human Immunodeficiency Virus
35. Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation
36. Gastrointestinal and Hepatic Manifestations of Systemic Diseases
37. Vascular Disorders of the Gastrointestinal Tract
38. Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm
39. Gastrointestinal and Hepatic Disorders in the Pregnant Patient
40. Radiation Injury
41. Preparation for and Complications of GI Endoscopy

Section V. Esophagus
42. Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus
43. Esophageal Neuromuscular Function and Motility Disorders
44. Gastroesophageal Reflux Disease
45. Barrett's Esophagus
46. Esophageal Disorders Caused by Medications, Trauma, and Infection
47. Esophageal Tumors
Section VI. Stomach and Duodenum
48. Anatomy, Histology, and Developmental Anomalies of the Stomach and Duodenum
49. Gastric Neuromuscular Function and Neuromuscular Disorders
50. Gastric Secretion
51. Helicobacter pylori Infection
52. Gastritis
53. Peptic Ulcer Disease
54. Adenocarcinoma of the Stomach and Other Gastric Tumors

Section VII. Pancreas
55. Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas
56. Pancreatic Secretion
57. Hereditary, Familial, and Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood
58. Acute Pancreatitis
59. Chronic Pancreatitis
60. Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors
61. Endoscopic Treatment of Pancreatic Disease

Section VIII. Biliary Tract
62. Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract
63. Biliary Tract Motor Function and Dysfunction
64. Bile Secretion and the Enterohepatic Circulation
65. Gallstone Disease
66. Treatment of Gallstone Disease
67. Acalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps
68. Primary Sclerosing Cholangitis and Recurrent Pyogenic Cholangitis
69. Tumors of the Bile Ducts, Gallbladder, and Ampulla
70. Endoscopic and Radiologic Treatment of Biliary Disease

Section IX. Liver71. Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver
72. Liver Physiology and Energy Metabolism
73. Liver Chemistry and Function Tests
74. Overview of Cirrhosis
75. Hemochromatosis
76. Wilson Disease
77. Other Inherited Metabolic Disorders of the Liver
78. Hepatitis A
79. Hepatitis B
80. Hepatitis C
81. Hepatitis D
82. Hepatitis E
83. Hepatitis Caused by Other Viruses
84. Bacterial, Parasitic, and Fungal Infections of the Liver, including Liver Abscess
85. Vascular Diseases of the Liver
86. Alcoholic Liver Disease
87. Nonalcoholic Fatty Liver Disease
88. Hepatic Drug Metabolism and Liver Disease Caused by Drugs
89. Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal Preparations
90. Autoimmune Hepatitis
91. Primary Biliary Cirrhosis
92. Portal Hypertension and Variceal Bleeding
93. Ascites and Spontaneous Bacterial Peritonitis
94. Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease
95. Acute Liver Failure
96. Hepatic Tumors and Cysts
97. Liver Transplantation

Section X. Small and Large Intestine
98. Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine
99. Small Intestinal Motor and Sensory Function and Dysfunction
100. Colonic Motor and Sensory Function and Dysfunction
101. Intestinal Electrolyte Absorption and Secretion
102. Digestion and Absorption of Dietary Fat, Carbohydrate, and Protein
103. Intestinal Digestion and Absorption of Micronutrients
104. Maldigestion and Malabsorption
105. Small Intestinal Bacterial Overgrowth
106. Short Bowel Syndrome
107. Celiac Disease
108. Tropical Diarrhea and Malabsorption
109. Whipple's Disease
110. Infectious Enteritis and Proctocolitis
111. Food Poisoning
112. Antibiotic-Associated Diarrhea and Clostridium difficile Infection
113. Intestinal Protozoa
114. Intestinal Worms
115. Crohn's Disease
116. Ulcerative Colitis
117. Ileostomy, Colostomy, and Pouches
118. Intestinal Ischemia
119. Intestinal Ulcerations
120. Appendicitis
121. Diverticular Disease of the Colon
122. Irritable Bowel Syndrome
123. Intestinal Obstruction
124. Ileus and Pseudo-obstruction
125. Tumors of the Small Intestine
126. Colonic Polyps and Polyposis Syndromes
127. Colorectal Cancer
128. Other Diseases of the Colon and Rectum
129. Diseases of the Anorectum

Section XI. Additional Treatments for Patients with Gastrointestinal and Liver Disease
130. Probiotics and Fecal Microbiota Transplantation
131. Complementary and Alternative Medicine
132. Palliative Care for Patients with Gastrointestinal and Hepatic Disease

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