STATIN-ASSOCIATED MUSCLE SYMPTOMS

Chapter 1. Introduction
Chapter 2. Do Statin-Associated Muscle Symptoms (SAMS) Exist?
Chapter 3. The Clinical Presentation of SAMS
Chapter 4. Definitions of SAMS
Chapter 5. The Patient’s Perspective of SAMS
Chapter 6. Psychosocial, Emotional, and Societal Factors Influencing Perceptions and Experiences of SAMS
Chapter 7. Prevalence of SAMS in Observational and Clinical Trials
Chapter 8. Risk factors for SAMS
Chapter 9. Clinical Trials of Treatments for SAMS
Chapter 10. Clinical Management of SAMS
Chapter 11. Effects of Statins on Exercise Performance and Exercise Training
Chapter 12. Genetic Risk Factors for SAMS
Chapter 13. The Role of the Mitochondria in SAMS
Chapter 14. The Role of Energy Metabolism in SAMS
Chapter 15. Vitamin D and SAMS
Chapter 16. Coenzyme Q 10 and SAMS
Chapter 17. Diagnosing SAMS
Chapter 18. The Clinical and Financial Cost of SAMS
Chapter 19. The Interaction of Statins and Inherited Muscle Disease
Chapter 20. The Differential Diagnosis of SAMS
Chapter 21. Statin-Associated Inflammatory Myositis and Other Inflammatory Conditions
Chapter 22. Managing Statin Rhabdomyolysis
Chapter 23. Future Directions: Critical Questions and Research Approaches to Improving Understanding and Treatment of SAMS.

This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.

Features
• Examines both sides of the debate on whether statin-related muscle symptoms exist
• Discusses risk factors, diagnosis and differential diagnosis, clinical presentations, and management
• Highlights the psychosocial, emotional, and societal factors influencing patients’ perceptions and experiences of SAMS
• Presents the results of observational and clinical trials on the prevalence and treatment of SAMS