STRUCTURE-FUNCTION RELATIONSHIPS IN VARIOUS RESPIRATORY SYSTEMS. CONNECTING TO THE NEXT GENERATION

• Part I Respiratory control system
1.Anatomy and physiology of respiratory control system
2.Anatomy and physiology of chemical regulatory mechanisms in respiration
3.Coordination of swallowing and breathing
• Part IIUpper airway
4.Anatomy and function of upper airway during sleep
5.Instability of upper airway during anesthesia and sedation
• Part III Lower airway
6.Convective and Diffusive Mixing in Lower and Acinar Airways
7.Radiological evaluation of lower airway dimensions deciding ventilatory dynamics
8.Functional properties of lower airway estimated by oscillometry
• Part IV Acinus
9.Inhomogeneous distribution of ventilation-perfusion (VA/Q) and diffusing capacity-perfusion (D/Q) in the lung
10.Physiological Basis of Effective Alveolar-Arterial O2 Difference (AaDO2) and Effective Physiological Dead Space (VD/VT)
11.Oxygen transport fro air to tissues as an integrated system
• Part VAlveolar wall
12.Pathophysiological and clinical implication of diffusing capacity for CO (DLco) and Krogh factor (Kco)
13.Basic perspective of simultaneous measurement of DLCO and DLNO
14.Reference equations for simultaneously measured DLCO and DLNO
15.Differential diagnosis based on newly developed indicator of DLNO/DLCO
16.Clinical significance of simultaneous measurements of DLCO and DLNO: Can DLCO and DLNO differentiate various kinds of lung diseases?.

This book elucidates the morphological backgrounds of various functional parameters of the human respiratory system, including the respiratory control system, dynamics of the upper and lower airways, gas transport and mixing in the lower airways, gas exchange in the acinus, and gas transfer through the alveolar wall. Presenting the latest findings on the interrelationships between morphology and physiology in the respiratory system, the book’s goal is to provide a foundation for further exploring structure-function relationships in various respiratory systems, and to improve both the quality of basic science, and that of clinical medicine targeting the human respiratory system.Edited and written by internationally recognized experts, Structure-Function Relationships in Various Respiratory Systems offers a valuable asset for all physicians and researchers engaging in clinical, physiological, or morphological work in the field of respiration. Moreover, it provides a practical guide for physicians, helping them make more precise pathophysiological decisions concerning patients with various types of lung disease, and will be of interest to respiratory physiologists and respiratory morphologists.

Features
• Elucidates the morphological backgrounds of various functional parameters of the respiratory system
• Presents the latest findings on the interrelationships between morphology and physiology in the respiratory system
• A valuable asset for all physicians and researchers engaged in clinical, physiological, or morphological work in the field of respiration

Author
Kazuhiro Yamaguchi, MD, PhD. Department of Respiratory Medicine, Tokyo Medical University, Tokyo, Japan. Division of Respiratory Medicine, Tohto Clinic, Kenko-Igaku Association, Tokyo, Japan