TEXTBOOK OF PEDIATRIC RHEUMATOLOGY, 7TH EDITION

Section 1: Basic Concepts and Fundamentals

1. Pediatric Rheumatology: the Study of Rheumatic Diseases in Childhood and Adolescence

2. Structure and Function

3. Immunology: Building Blocks

4. Immunology: Translation

5. Integrative Genomics

Evaluation

6. TRIAL DESIGN, MEASUREMENT, AND ANALYSIS OF CLINICAL INVESTIGATIONS

7. Assessment of Health Status

8. Pain and its Assessment

9. Radiology

10. Laboratory Investigations

Management

11. Managing Children with Rheumatic Diseases

12. Pharmacology Non-Biologics

13. Pharmacology Biologics

14. Occupational and Physical Therapy for Rheumatic Diseases

Section 2: Chronic Arthritis

15. Chronic Arthritis in Children and Adolescence

16. Systemic Juvenile Idiopathic Arthritis

17. POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

18. OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

19. Enthesitis Related Arthritis

20. Juvenile Psoriatic Arthritis

21. Arthropathies of Inflammatory Bowel Disease

22. UVEITIS IN JUVENILE IDIOPATHIC ARTHRITIS

Section 3: Systemic Connective Tissue Diseases

23. Systemic Lupus Erythematosus

24. Antiphospholipid Syndrome

25. Neonatal Lupus

26. Juvenile Dermatomyositis

27. Systemic Sclerodermas

28. Localized Sclerodermas

29. MIXED CONNECTIVE TISSUE DISEASE AND UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE

30. Sjogren's Syndrome

31. Raynaud Phenomenon

Section 4: Vasculitis

32. Vasculitis And Its Classification

33. Leukocytoclastic Vasculitis: Henoch-Schönlein Purpura, and Hypersensitivity Vasculitis

34. POLYARTERITIS NODOSA

35. Kawasaki Disease

36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis

37. CNS Vasculitis

38. Other Vasculitis

39. PEDIATRIC SARCOIDOSIS

40. Behcet Disease

Section 5: Arthritis Related to Infection

41. Infectious Arthritis and Osteomyelitis

42. Lyme Disease

43. Reactive Arthritis

44. Rheumatic Fever

45. Musculoskeletal Manifestations of Systemic Disease

46. Immunodeficiencies

47. Systemic Autoinflammatory Diseases

48. Autoinflammatory Bone Disorders

49. Macrophage Activation Syndrome

50. Malignancies

Section 6: Noninflammatory Musculoskeletal Pain

51. Noninflammatory Musculoskeletal Pain

52. Pain Amplification Syndromes

53. Disorders of Bone Mineralization

54. Primary Disorders of Connective Tissue

Matchless in reputation, content, and usefulness, Textbook of Pediatric Rheumatology, 7th Edition, is a must-have for any physician caring for children with rheumatic diseases. It provides an up-to-date, global perspective on every aspect of pediatric rheumatology, reflecting the changes in diagnosis, monitoring, and management that recent advances have made possible - all enhanced by a full-color design that facilitates a thorough understanding of the science that underlies rheumatic disease.

Features:
- Get an authoritative, balanced view of the field with a comprehensive and coherent review of both basic science and clinical practice.
- Apply the knowledge and experience of a who’s who of international experts in the field.
- Examine the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, including the presentation, differential diagnosis, course, management, and prognosis of every major condition.
- Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders.

New To This Edition:
- Keep current with the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies.
- Increase your knowledge with three all-new chapters on laboratory investigations, CNS vasculitis, and other vasculitides.
- Understand the evolving globalization of pediatric rheumatology, especially as it is reflected in the diagnosis and management of childhood rheumatic diseases in the southern hemisphere.
- Choose treatment protocols based on the best scientific evidence available today.

Authors
Ross E Petty, MD, PhD, FRCPC, Professor, Division of Rheumatology, University of British Columbia; Professor of Pediatrics, Department of Pediatrics, British Columbia Children's Hospital, Vancouver, British Columbia, Canada; Ronald M. Laxer, MD, FRCPC, Professor, Pediatrics and Medicine, University of Toronto, Division of Rheumatology, THe Hospital for Sick Children, Toronto, Ontario, Canada; Carol B Lindsley, MD, FAAP, MACR, Professor of Pediatric Rheumatology, The University of Kansas, Kansas City, Kansas and Lucy Wedderburn, MD, PhD, FRCP, Professor of Pediatric Rheumatology, Institute of Child Health, University College London, Consultant Rheumatologist, Great Ormond Street Children's Hospital, London, UK

CONTENTS:
Section 1: Basic Concepts and Fundamentals
1. Pediatric Rheumatology: the Study of Rheumatic Diseases in Childhood and Adolescence
2. Structure and Function
3. Immunology: Building Blocks
4. Immunology: Translation
5. Integrative Genomics
Evaluation
6. TRIAL DESIGN, MEASUREMENT, AND ANALYSIS OF CLINICAL INVESTIGATIONS
7. Assessment of Health Status
8. Pain and its Assessment
9. Radiology
10. Laboratory Investigations
Management
11. Managing Children with Rheumatic Diseases
12. Pharmacology Non-Biologics
13. Pharmacology Biologics
14. Occupational and Physical Therapy for Rheumatic Diseases
Section 2: Chronic Arthritis
15. Chronic Arthritis in Children and Adolescence
16. Systemic Juvenile Idiopathic Arthritis
17. POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS
18. OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS
19. Enthesitis Related Arthritis
20. Juvenile Psoriatic Arthritis
21. Arthropathies of Inflammatory Bowel Disease
22. UVEITIS IN JUVENILE IDIOPATHIC ARTHRITIS
Section 3: Systemic Connective Tissue Diseases
23. Systemic Lupus Erythematosus
24. Antiphospholipid Syndrome
25. Neonatal Lupus
26. Juvenile Dermatomyositis
27. Systemic Sclerodermas
28. Localized Sclerodermas
29. MIXED CONNECTIVE TISSUE DISEASE AND UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE
30. Sjogren""s Syndrome
31. Raynaud Phenomenon
Section 4: Vasculitis
32. Vasculitis And Its Classification
33. Leukocytoclastic Vasculitis: Henoch-Schönlein Purpura, and Hypersensitivity Vasculitis
34. POLYARTERITIS NODOSA
35. Kawasaki Disease
36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis
37. CNS Vasculitis
38. Other Vasculitis
39. PEDIATRIC SARCOIDOSIS
40. Behcet Disease
Section 5: Arthritis Related to Infection
41. Infectious Arthritis and Osteomyelitis
42. Lyme Disease
43. Reactive Arthritis
44. Rheumatic Fever
45. Musculoskeletal Manifestations of Systemic Disease
46. Immunodeficiencies
47. Systemic Autoinflammatory Diseases
48. Autoinflammatory Bone Disorders
49. Macrophage Activation Syndrome
50. Malignancies
Section 6: Noninflammatory Musculoskeletal Pain
51. Noninflammatory Musculoskeletal Pain
52. Pain Amplification Syndromes
53. Disorders of Bone Mineralization
54. Primary Disorders of Connective Tissue