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90,90 €1. General Overview
2. Prion Diseases
3. Alzheimer’s disease: towards a quantitative biological approach in describing its natural history and underlying mechanisms
4. Neurodegeneration and the ordered assembly of Tau
5. ALS and Other TDP43 Proteinopathies
6. Parkinson’s Disease and Other Synucleinopathies
7. Huntington’s Disease and Other Polyglutamine Disorders
8. Prion-like propagation in Neurodegenerative Diseases
9. Neurodegenerative Diseases as Protein Folding Disorders
10. Heat shock proteins and protein quality control in Alzheimer's disease
11. Neurodegenerative Diseases and Autophagy
12. Neurodegenerative Diseases and Axonal Transport
13. Mitochondrial Function and Neurodegenerative Diseases
14. Neurodegenerative Diseases and Non-cell autonomous toxicity
15. Neurodegenerative Diseases and RNA-mediated toxicity
16. Neuroinflammation in Age-Related Neurodegenerative Diseases
17. Neurodegenerative Diseases and the Aging Brain
• Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular features
• Focuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegeneration
• Details features, advantages and limitations of animal models, as well as prospects for therapeutic development
• Authored by internationally recognized leaders in the field
• Includes illustrations that help clarify and consolidate complex concepts
Author
Michael S. Wolfe, PhD, Professor of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
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