THE TEXTBOOK OF NANONEUROSCIENCE AND NANONEUROSURGERY. 2ND EDITION

1. From Nanotechnology to Nanotechnology/Nanoneurosurgery and Nanobioelectronics: A Historical Review of Milestones
2. Nanoneurology and Nanoneurosurgery
3. Nanopolymers and Nanoconjugates for Central Nervous System Diagnostics and Therapies
4. Micelles, Liposomes, and Extracellular Vesicles: Lipid Nanovesicles for Central Nervous System Drug Delivery
5. Peptide- and Protein-Based Nanoparticles
6. Endohedral Metallofullerenes, Iron Oxide Agents, and Gold Nanoparticles for Brain Imaging
7. Carbon-Based Nanoplatforms: Types and Applications in Neurological Disorders
8. Dendritic and Nanostructured Boron Compounds for Cancer Therapy
9. Ligand-Based Targeting of Therapeutic and Imaging Agents for Cancer
10. Nano-Assisted Immune-Based Targeting in Cancer
11. Directed Drug Convection Using Magnetic Nanoparticles as Therapeutic Carriers Meeting the Challenge of Specific Brain Pharmacotherapeutics, Non-ligand-Based Central Nervous System Targeting, Including Magnetic Focusing
12. Intralesional and Intraparenchymal Convection-Enhanced Delivery of Nanoparticles
13. Transport of Nanoparticles Across Blood–Brain Barrier
14. Nanomedicine Treatment Strategies That Exploit Unique Characteristics of Tumor Vasculature and Microenvironment
15. Focused Ultrasound for Non-invasive Neuromodulation
16. Nanostructured Surfaces for Intracerebral Neurotransmitter Recording
17. Therapy for Neuropathic Lysosomal Storage Diseases
18. Nanotechnology for Cerebral Aneurysm Treatment
19. Applications and Recent Advances of Nanotechnology and Nanomedicine in the Diagnosis and Therapy of Stroke
20. Molecular Medical Devices for Nanoneurosurgery
21. Applications of Nanotechnology in Epilepsy
22. Applications of Nanotechnology to Diseases of the Spine
23. Nanoparticle-Based Treatment and Imaging of Brain Tumors Potentials and Limitations
24. Tumor-Targeted Nanodrugs for the Treatment of Primary Brain Tumors
25. Application of Nanotechnology in the Diagnosis and Treatment of Brain Metastases
26. Nanotechnology in Brain Tumors: Neurosurgical Perspectives
27. Using Nanoparticles in Diagnosis and Treatment of CNS Infection
28. Nanotechnology in the Prevention and Treatment of Neurological Disorders
29. Nanomedicine in Demyelinating Disease Application to Diagnosis and Therapy in Multiple Sclerosis
30. Applications of Nanotechnology in Degenerative Disorders of the Brain
31. Brain–Machine Interface and Rehabilitation
32. Nanobioelectronics for Noninvasive Neural Therapy
33. In Vitro and In Vivo Techniques to Assess Neurotoxicity of Nanoparticles
34. Nanorobotics for Neurosurgery
35. Micro- and Nanotechnologies in Nerve Repair
36. Nanotechnology Applications to Pediatric Neurosurgery
37. Application of Nanotechnology for Cerebrovascular and Skull Base Disorders
38. Application of Nanotechnology in Acquired Brain Injuries
39. microRNAs Mediate Signaling Pathways in Alzheimer’s Disease: Biomarkers and Therapeutic Targets
40. Retinal Neuromodulation as an Influence on Brain Function by Applying Nanoneuroscience Discoveries
41. Bridging the Gap: Nanotechnology’s Impact on Neuroscience—A Systematic Review of Clinical Trial
42. Nanostructured Boron and Gadolinium Compounds for Neutron Capture Therapy (NCT)
43. Applications of 3D Bioprinting in Nanoneuroscience
44. Nano-Neurosurgery: Nanoparticle-Guided Strategies
45. Food and Drug Administration Regulatory Framework for Nanodrugs and Nanodevices and the Combination
46. Nanoneuroscience and Nanoneurosurgery: A Key Component of Presidential Brain Mapping and Cancer Moonshot, Neurotechnology and Brain Mapping Day Policy Initiatives

Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery, 2nd edition presents a state-of-the-art review of the field, providing current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology.

The text also reviews the latest regulatory guidelines that influence the translation of nanotechnological research from the laboratory to the clinic, as well as the most recent information on biodevices and pharmaceutical spinoffs. It highlights presidential and congressional initiatives and programs that may significantly impact the field in the near future. Chapters discuss the latest science and technologies which are applied to diagnosis and treatment of neurological disorders as well as regulatory issues that impact product development.

This volume describes advances that have already been translated to the clinic or hold significant promise for future application in nanoneurosurgery, as well as their potential impact. A full-color text, the book contains contributions by more than 120 researchers, original and descriptive illustrations, and more than 3,000 references. Offering broad coverage of nanotechnological applications in diverse areas and addressing FDA regulation and healthcare policy, this volume provides a foundation of ideas and methods for scientists and physicians to devise successful, less invasive procedures for future treatment of nervous system disorders