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135,85 €An underlying principle of developmental biology is that invertebrate species, such as flies or fish, employ essentially the same signaling systems to establish the body plan as vertebrates. While the mouse may be the animal model of choice for studies of vertebrate development, the fact that most of mouse embryonic development occurs in the mother's uterus makes it quite difficult to study. The zebrafish, which produces large numbers of embyros that develop outside the mother's body, has emerged as the preeminent genetic system for developmental analysis.
This volume of Methods in Cell Biology, the second of two parts on the subject of zebrafish, provides a comprehensive compendium of laboratory protocols and reviews covering all the new methods developed since 1999.
Features:
• Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls
• Illustrates many techiques in full-color
• Summarizes the Zebrafish Genome Project
Authors
• H. William Detrich, III, Northeastern University, Boston, MA, USA;
• Monte Westerfield, Institute of Neuroscience, University of Oregon, Eugene, OR, USA
• Leonard Zon, Boston Children's Hospital / HHMI, Boston, MA, USA
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